DreEX0002300 @ danRer10
Exon Skipping
Gene
ENSDARG00000045199 | CAPN1 (1 of 2)
Description
calpain 1, (mu/I) large subunit [Source:HGNC Symbol;Acc:HGNC:1476]
Coordinates
chr7:6567228-6570115:-
Coord C1 exon
chr7:6570041-6570115
Coord A exon
chr7:6567875-6568035
Coord C2 exon
chr7:6567228-6567388
Length
161 bp
Sequences
Splice sites
3' ss Seq
TGTGTGTGTCTCTCCATCAGGAT
3' ss Score
10.82
5' ss Seq
CAGGTATCA
5' ss Score
7.33
Exon sequences
Seq C1 exon
CTCTCGCGAATGGGACAATGTGGACCGCTCCGTCCGGGGCCGATTACAGAACCGCAGCGAGGACGGAGAGTTCTG
Seq A exon
GATGTCGTTCAGTGATTTTCTGCGCGAGTTCACCCGTTTGGAAATCTGTAACCTGACGGCGGACGCTCTCCAGGCCAGTCAGGTGAAGAAGTGGAGCACCGCCAACTATAACGGCGAGTGGAGGAGAGGAAGCACTGCAGGTGGCTGCAGGAACTATCCAG
Seq C2 exon
CAACATTCTGGATCAACCCGCAGTTCAAGGTGGCCCTGAAACACCCGGATTCTCCCGGCCAATCAGAGTGCAGCTTCCTGGTGGCGCTGATGCAGAAGGACCGCAGGAAGAAGAGAAGAGAAGGGCAGGACATGGAGACTATCGGATTCGCCATTTATGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000045199-'11-12,'11-11,14-12
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.038 A=0.000 C2=0.071
Domain overlap (PFAM):
C1:
PF0064816=Peptidase_C2=FE(8.3=100)
A:
PF0064816=Peptidase_C2=PD(6.3=34.5),PF0106717=Calpain_III=PU(15.8=43.6)
C2:
PF0106717=Calpain_III=FE(34.6=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGGACAATGTGGACCGCTC
R:
CTCATAAATGGCGAATCCGATAGTCT
Band lengths:
226-387
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]