DreEX0051144 @ danRer10

Exon Skipping

Gene

ENSDARG00000052139 | notch3

Description

notch 3 [Source:ZFIN;Acc:ZDB-GENE-000329-5]

Coordinates

chr3:53276902-53280391:-

Coord C1 exon

chr3:53280279-53280391

Coord A exon

chr3:53279646-53280175

Coord C2 exon

chr3:53276902-53276999

Length

530 bp

Sequences

Splice sites

3' ss Seq

CATTATCGTCTCTTTTTTAGGGG

3' ss Score

10.06

5' ss Seq

CAAGTAAGT

5' ss Score

10.08

Exon sequences

Seq C1 exon

GACGAGGGTGTCAAAGTAGATTCAGCGTGTGCGAGTCTCAGCCCTGTAAAAATGGAGGAGTATGTTCCTTGTCTGGCAGCTCCCCACCAGGATACTCTTGCACTTGTCAGCTT

Seq A exon

GGGTACGCAGGTTCTAACTGTGAGAGGAGCATGAACTGCAAAGAGCTGCCTTGCTACAATGGAGGCAGTTGCACTCTCACCACACGAGGGGCACGTTGTACTTGCATTCAGGGCTTTGGTGGGCCATTGTGTCAGCACCGCAGCAATGACGGCTGCTCCTCCAAGCCATGCCACAATGGAGGCTTATGTACAGAGGAAACCAGCTATCCATTTTTTCACTGCCAGTGCACCAATGGCTGGAAAGGCAAACGATGTGAACAGAAAACTGGGTCATCGGCTCCACTTCCTTCTCCTTGCCCTATTGCTGACTGCTTCAGCAAGGCCAATGACGGTGTGTGTGACAAAGAATGCAACTCCTTAGACTGCCGCTGGGACGGAGGTGACTGTTCTCTTGCTGTAAACCCCTGGGCACGCTGTGCAGACCCTCGATGCTGGCGGCTCTTCAATAACAGCCAATGTGACGAGTTTTGCAATAACGCAGAGTGCCTGTTCGATAATTTCGACTGCATAAACAAAGAGAAAGTCTGCAA

Seq C2 exon

GAAAGTCAGCATTGCACTGGGCAGCAGCAGTCAATAACGTTGAAGCTACTATTGCCTTGTTGAAGAATGGTGCCAATAAAGATATGCAAGACCTCAAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSDARG00000052139_MULTIEX1-12/19=11-C2

Average complexity

C3

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.000 A=0.000 C2=0.030

Domain overlap (PFAM):

C1:

PF0000822=EGF=PD(6.1=5.3),PF0000822=EGF=PU(79.4=71.1)

A:

PF0000822=EGF=PD(14.7=2.8),PF0000822=EGF=WD(100=17.5),PF0000822=EGF=WD(100=18.6),PF0006612=Notch=WD(100=20.3),PF0006612=Notch=WD(100=20.9),PF0006612=Notch=PU(15.0=3.4)

C2:

PF127962=Ank_2=FE(34.4=100)

Main Inclusion Isoform:

ENSDARP00000068420