DreEX6014878 @ danRer10
Exon Skipping
Gene
ENSDARG00000075737 | A2ML1 (6 of 13)
Description
alpha-2-macroglobulin-like 1 [Source:HGNC Symbol;Acc:HGNC:23336]
Coordinates
chr3:130759-131769:-
Coord C1 exon
chr3:131607-131769
Coord A exon
chr3:131279-131463
Coord C2 exon
chr3:130759-130980
Length
185 bp
Sequences
Splice sites
3' ss Seq
CCCCTCTCCTGTTCTCTTAGGTA
3' ss Score
10.52
5' ss Seq
CAGGTGACT
5' ss Score
6.6
Exon sequences
Seq C1 exon
GATCCTGTCATTACTAAGGCTCTGTCGTTTTTGAGGCCTCTTGTTGGGAATCTGGGGAACACCTATGTCACTGCTCTGCTCGCCTACACCTTCAGTCTGGCTGGAGAGACCAGCACTCGAGCACAGCTTTTAAATTCCTTGCGAAACACTGCCATTTCTGAAG
Seq A exon
GTACTACTCTCCACTGGTCTCAGACTACATCAGGGGACACTCTGGCAGTGGAGATCAGTGCATATGTGCTGTTAGCAGTTCTCAATGTACAGCCTGTGACCACTGCTACACTGGGCTATGCTAACCGCATTGTCAACTGGCTTGTGGCCCAGCAGAATCCCTATGGTGGTTTCACCTCCACTCAG
Seq C2 exon
GACACCGTGGTGGCTCTTCAGGCTATGGCTTTATATGCTAGTCTCGTGTTCAGTTCTGGAGGTTCCAGCACAGTTACCGTTCAGTCCTCAGTGCCAGCAGGAGATGTGTACAACTTTGCTGTGACTCCCAACAACCGCTTGCTGTATCAGGAGAGTCCACTCAACAACTTTCCAGGCACATATAGTGTTGTAGCATCGGGATCCACTTGTGTGTCAGTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000075737-'29-29,'29-28,30-29=AN
Average complexity
A_S
Mappability confidence:
88%=100=75%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.016 C2=0.000
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=FE(23.1=100)
A:
PF076789=A2M_comp=FE(26.1=100)
C2:
PF076789=A2M_comp=PD(5.6=17.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGGGAATCTGGGGAACACCT
R:
GGTTGTTGGGAGTCACAGCAA
Band lengths:
256-441
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]