DreEX6014990 @ danRer10
Exon Skipping
Gene
ENSDARG00000078183 | A2ML1 (10 of 13)
Description
alpha-2-macroglobulin-like 1 [Source:HGNC Symbol;Acc:HGNC:23336]
Coordinates
chr3:3680647-3681237:+
Coord C1 exon
chr3:3680647-3680823
Coord A exon
chr3:3680934-3681009
Coord C2 exon
chr3:3681081-3681237
Length
76 bp
Sequences
Splice sites
3' ss Seq
GGATGTTTGGACTGGGACAGGAT
3' ss Score
1.39
5' ss Seq
ATGGTGCGT
5' ss Score
8.27
Exon sequences
Seq C1 exon
GGGACATCATGGGTCGTGCACTGAAGAATTTGGCAAACTTGCTACAGATGCCTTATGGCTGTGGAGAACAGAACATGATCATTCTCGCTCCCAATATTTACACTCTGCAGTATCTGAAAGTAACGGCACAGCTCACCCCAGCCATCCAAGACACTGCCGCGAGTTATCTTCTGAGTG
Seq A exon
GATATCAAAGAGAGCTGAACTACAGGCACAGCGACGGTTCATTCAGCACTTTTCCTTATTCACCATCCAATACATG
Seq C2 exon
GTTGACTACCTTTGTCATGAGGACTTTTGGCCTAGCAAGGAACTTCACCTACATAGATCCCAATGTCCTTCAGAGCGCAAAGGACTGGTTGATTGGCACGCAGGGTTCAGATGGTTGTTTTGTGCAACAGGGGACTCTGTACCACAAAGACATGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000078183-'29-34,'29-33,30-34=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF105694=Thiol-ester_cl=WD(100=51.7),PF076789=A2M_comp=PU(0.4=1.7)
A:
PF076789=A2M_comp=FE(10.7=100)
C2:
PF076789=A2M_comp=FE(22.2=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAAGACACTGCCGCGAGTTAT
R:
TACAGAGTCCCCTGTTGCACA
Band lengths:
172-248
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]