DreEX6076183 @ danRer10
Exon Skipping
Gene
ENSDARG00000013892 | sorl1
Description
sortilin-related receptor, L(DLR class) A repeats containing [Source:ZFIN;Acc:ZDB-GENE-050208-22]
Coordinates
chr15:21638423-21640017:-
Coord C1 exon
chr15:21639926-21640017
Coord A exon
chr15:21638653-21638899
Coord C2 exon
chr15:21638423-21638561
Length
247 bp
Sequences
Splice sites
3' ss Seq
GATCTGCATGTCTCTCTTAGCTT
3' ss Score
5.85
5' ss Seq
AAGGTAGGC
5' ss Score
10.08
Exon sequences
Seq C1 exon
GTGTCCAACTCTGATGGAGACCTGAGACGCACTCTGGTCAACTCTTCAGTGGTGGACCAGCCTCGAGCCCTGGCACTCATGCCAGCAGAGAG
Seq A exon
CTTGATGTTTTGGACAGATTGGGGTGATCGTGCAGCAGGCGTCTACCGCAGCTGGATGGACGGCTCGAACATCTCCTGCATTGTGTCAGAGGGAGTCCGCTGGCCTAATGGCATTACAGCTGATGAGTCGTGGCTGTACTGGACAGAGGCATATGGAGACCGCATTGAACGAGCTGATTTTAATGGAGGAAGCCGCACTGTCATAATGGAGGGCCTGCCTCATCCTTACGCTATTGCTGTTTTTAAG
Seq C2 exon
AATGACCTGTACTGGGATGACTGGTCCAGAATGGGAATCTTCAAAGCACCGAAATCAGGCTCACCGGACAGTGAGTTGATAGTGGGCCGCCTAACAGGAGTAATGGACCTCAAGATCTTCTACAAGGGAAAAAACAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000013892-'21-25,'21-24,22-25=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(64.3=87.1),PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
PF0005812=Ldl_recept_b=WD(100=51.8),PF0005812=Ldl_recept_b=WD(100=47.0)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCAACTCTGATGGAGACCTGA
R:
TTTCCCTTGTAGAAGATCTTGAGGT
Band lengths:
220-467
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]