DreEX6076184 @ danRer10
Exon Skipping
Gene
ENSDARG00000013892 | sorl1
Description
sortilin-related receptor, L(DLR class) A repeats containing [Source:ZFIN;Acc:ZDB-GENE-050208-22]
Coordinates
chr15:21635460-21638899:-
Coord C1 exon
chr15:21638653-21638899
Coord A exon
chr15:21638423-21638561
Coord C2 exon
chr15:21635460-21635633
Length
139 bp
Sequences
Splice sites
3' ss Seq
TGGTGTCTTTGTTGGTGTAGAAT
3' ss Score
6.86
5' ss Seq
GAGGTTAGA
5' ss Score
4.15
Exon sequences
Seq C1 exon
CTTGATGTTTTGGACAGATTGGGGTGATCGTGCAGCAGGCGTCTACCGCAGCTGGATGGACGGCTCGAACATCTCCTGCATTGTGTCAGAGGGAGTCCGCTGGCCTAATGGCATTACAGCTGATGAGTCGTGGCTGTACTGGACAGAGGCATATGGAGACCGCATTGAACGAGCTGATTTTAATGGAGGAAGCCGCACTGTCATAATGGAGGGCCTGCCTCATCCTTACGCTATTGCTGTTTTTAAG
Seq A exon
AATGACCTGTACTGGGATGACTGGTCCAGAATGGGAATCTTCAAAGCACCGAAATCAGGCTCACCGGACAGTGAGTTGATAGTGGGCCGCCTAACAGGAGTAATGGACCTCAAGATCTTCTACAAGGGAAAAAACAGAG
Seq C2 exon
GTCAGAATGCCTGCGCAGATCAGCCATGCAGTCTTCTGTGCCTTCCCCAGCCTGGAAACCAGCGTCACTGTGTTTGTCCCGATGGGGTTCCCACCAGCGTCCTGCCCTCAGGAGAGCGTCAGTGCCAGTGTCCCAGCGGATACCAACTACACAACAATACATGTGTCAAGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000013892-'22-26,'22-25,23-26=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=51.8),PF0005812=Ldl_recept_b=WD(100=47.0)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCTGCATTGTGTCAGAGGGA
R:
ATCGGGACAAACACAGTGACG
Band lengths:
257-396
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]