DreEX6093193 @ danRer10
Exon Skipping
Gene
ENSDARG00000074808 | MEGF6 (1 of 2)
Description
multiple EGF-like-domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr11:41149108-41153153:-
Coord C1 exon
chr11:41153028-41153153
Coord A exon
chr11:41149356-41149478
Coord C2 exon
chr11:41149108-41149230
Length
123 bp
Sequences
Splice sites
3' ss Seq
CCTGTATTGACCATCATCAGTGG
3' ss Score
2.28
5' ss Seq
AAGGTAAAA
5' ss Score
8.38
Exon sequences
Seq C1 exon
CTGTTCAGTCCTGCGGCGTTGGGAATGGCGGCTGTGAGCATTTCTGTGTCCAGCAGACGGCGGGTCATGTCCAGTGTCGCTGCAGACCTGATTACAGACTGGACGCGGATGGAAAACACTGCACAT
Seq A exon
TGGTGAACCCGTGTGCGGAGCAGAATGGCGGATGTTCTCAGATGTGTCATAGGGATGGAGCTCAGGCCCGCTGTGAATGTCATCCAGGTTATCAGCTCGCTGAAGACGGCAAGACATGTGAAG
Seq C2 exon
ACATTGATGAGTGTGCGTTGGGTCAGACGGACTGTGCTCATGGCTGTCGTAACACCAGAGGATCCTTCATGTGTGTGTGTTCTGCTGCCTATGAGCTCGGGGTGGACGGTAAACAGTGCTATC
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000074808-'8-7,'8-6,9-7=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=86.0)
A:
PF146701=FXa_inhibition=WD(100=85.7),PF0764510=EGF_CA=PU(0.1=0.0)
C2:
PF0764510=EGF_CA=WD(100=95.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTCAGTCCTGCGGCGTTG
R:
TAGCACTGTTTACCGTCCACC
Band lengths:
245-368
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]