DreINT0025827 @ danRer10
Intron Retention
Gene
ENSDARG00000011188 | acvr2aa
Description
activin A receptor, type IIAa [Source:ZFIN;Acc:ZDB-GENE-980526-227]
Coordinates
chr9:25577272-25579091:-
Coord C1 exon
chr9:25578946-25579091
Coord A exon
chr9:25577387-25578945
Coord C2 exon
chr9:25577272-25577386
Length
1559 bp
Sequences
Splice sites
5' ss Seq
CAGGTTAGA
5' ss Score
5.94
3' ss Seq
GCTTTGTCTCGTGTTCACAGAGA
3' ss Score
8.94
Exon sequences
Seq C1 exon
AGTTCTCTGACGGACTACTTGAAGGCCAACGTAGTGACGTGGAACGAGCTGTGCCACATCGCTCAGACCATGGCTCGAGGACTGGCTTACTTGCACTCCGACTTCCCAGGACACAGAGATGGTCACAAACCAGCCATCGCACACAG
Seq A exon
GTTAGAAATGTATATCTGTCTCGTCTGCGTTTTTAGGTATTCGATCACAAGTGTTTAACAGACATGCATAATGTAAGTAAATTAAAAGTAAGTGAAAGGCATTATGGCAACTAGGATTTCAGTCATAACCTGTGTTTTGGGACAATGCAGTGGTGTATGAATACCTTATTTACGTCTGCTTTCTTCAGATTATGTCTCATTGAGACCATGTGTTAGGTTTGTAGAAGGAAAGTAATTATTGTGGCTTGTGGTCTTTTGTGGGTTTTTTGACGAAATAGGTGTTTACACTACTTCTAAAAGTTGTTTTTTAGACCACACTTTTAGTTGTATATTGCATGGCTCACTTGTAATCAGACTGACAAAAAGGCATTTAATACCACATTTAAACAGGCTTAATAAACAGTTTGCACCTTGAAAATATTGAAAAGTTAACAAATCTTAAGTCACAAATTGTTAGAAATCTGGATGGCATTCTTCTACCATTGGCATTGCAAAAAAAAAAAAAAAGGATTTTTTCCTCGTGTTTTTTTCTCTAAACTGTGGAAGTTTTGCATCCTGTTGAGTGTCTAAATATATTAAAATATCTTCATTCATTCATTTTCTTTTCGGCTTAGTCCCTTTATTATTTCGGGGTCGCCACAGTGGAATGAACCCCCAACTTATCCAGCATATGTTTTATGCAGCGGATGCCCTTCCAGCTGCAACCAATCTCTGCAAAACATCCATACACTTATTCACACTCATACACTACGTACAATTTAGCCTACCCAATTCACCTGTACCGCATGTCTTTGGCATGTGGTGGAAAATGAAGGACCCGGAGGAAACCCACGCGAACACAGGGAGAACATGCAAACTCCACACAGAAATGCCAACTGACCCAGCCGAGCCTCGAACCAGCGACCTTCTTACTGTGAGGCGACAGCACTACCTACTACGCCACTGCACTGCCTCAAAATATCTTATTAAAAGTTTTTTTTTTGACTGTCCTGCTTTTCGACTTACTGAAAGGGTCATGAAACCACTCTCAGTTCAAATCTACCTCAGAATTTTAAAAAAAATGGTTAAAAGATGCTCGACACAAACAAATCTGTTAAAATCACACAAAAAAAAGTACTTCAGGGTGTCTTGAACTTTAAATCTAGATAGGTTTCTTTAAATCATTGGGAGTGTTAAAGAAGGGTTTTTTTATCTGGACTATGAAAGCTTTGGACCCTGTTGACTGTCTGTAAAGGCAAAAATATCTTCAAAATATCTTTATTAAAAAACAATTTGGACTGTCCTGCTTTTCGACTCAAAGAATGTAAAGGGGTTTTTTTTTCTTAAAGCAAACTTGACAAAATATTATCATATATTTATTTATTTATGTAAAAGTCTGATGTAAATATCTTGTGCTTGTATTTGTTTAAATGGTTTTGTTGTTTCTTTATTATATTTCTATTTTTCAGTATTGTCAAGACATTAGCCAAAGTTATCATGCTATGTATAAAAGATACAGTACAATATATTCATCAATATAAGCCATTTTACCTTATTTAAGCTTTGTCTCGTGTTCACAG
Seq C2 exon
AGATTTCAAGAGCAAGAATGTATTGCTGAAGACAAACCTGACAGCCTGTATAGCTGATTTTGGATTGGCTTTAAAGTTTGAGGCTGGGAAGTCAGCTGGGGACACACATGGGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000011188:ENSDART00000129522:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.051
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(16.6=100)
A:
NA
C2:
PF0006920=Pkinase=FE(13.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGACGGACTACTTGAAGGCCA
R:
CTGCCCATGTGTGTCCCCA
Band lengths:
254-1813
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]