MmuINT0010617 @ mm10
Intron Retention
Gene
ENSMUSG00000052155 | Acvr2a
Description
activin receptor IIA [Source:MGI Symbol;Acc:MGI:102806]
Coordinates
chr2:48893507-48894780:+
Coord C1 exon
chr2:48893507-48893652
Coord A exon
chr2:48893653-48894665
Coord C2 exon
chr2:48894666-48894780
Length
1013 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGAA
5' ss Score
6.68
3' ss Seq
TTTTATTTTTATGTTTGAAGGGA
3' ss Score
6.92
Exon sequences
Seq C1 exon
GGCTCACTGTCAGACTTTCTTAAGGCTAATGTGGTCTCTTGGAATGAACTTTGTCATATTGCAGAAACCATGGCTAGAGGATTGGCATATTTACATGAGGATATACCTGGCTTAAAAGATGGCCACAAGCCTGCAATCTCTCACAG
Seq A exon
GTAGAACAAAATCTGTATTGTCTTTTCATCCAGCTCAAATGTTTACTACTTAAACTTTTAACTCTTGGAGTAAAATTTATTTTTGCAGTGATTATCCAATCATATTTGAAGAGGCAAAGACTTTTCAAGTTTTTAAAATTAGGTGAGATTGGCTAGGGTGTGTTTTGGTATGTACATGTTAATGTACATGTTAATCTTGTTAATAAAGTCTAATGATCCCATGTTTTAATTTGTGTAACTTCTGAAAGTATGTTTGAGAATAAAAGTGTATTTTCTCTATTTCAAAGGAGAAATGATTTTAACTCAAAATTTTGAGTTTAAAGACAATTTTTAGTAAATCCACAGTGATAGAATTAAGGATAAAGTATTTTCTCTGTCTTTTGGATGAATAAATATAACATTCATTCCTTGAGCTAAAGTAGAAGGGACCAACCAAGAGGAGACAGCTAGCTCTTGAGTAAAGAAATAGTGCTCATCAGTGAAATGACTGTTACAGTCTTAAAAAGGAAAAATATTTGTTTCTGGGAAATAAATTTAGTTTGCTATTATTTAACTTCCTTGGAATAATATGGGATTGAGTTGTCTTTCTATTCAGTTTTAAAATGGCTGTTTTAAAAGTCGGTATTAACATATTGATTTAGCAGATGTGTAGTTGAGTGTTACCAAACCATGACTTCTTTAGAAAGTCCTCTCCTTTCTTTCATGTTTATGAGTCCCCTAACTTATTAGTTATAGGGCCCTTTAAAATGTTTGTCAGTTGGTGTCTGGAGCATTTGACTCTACCTTCATCTTTTTGTAGAACTAAATGACTACTTCTAAGTGTACCTATTGATGAGAGCATAGACATGTTTGCTAGAGTTGTCTTTAAGTTGAACCAGATGAGGCACTCTTCTTTGCTCTAAATAAAGTTTCTTAGTTTTAAGTAACTTTATTTTTATATCATATTCTCCATGTATTCAGTAGAAAAATTTGAAAGATAACTTGCTTAAGATATTTTATTTTTATGTTTGAAG
Seq C2 exon
GGACATCAAAAGTAAAAATGTGCTGTTGAAAAACAATCTGACAGCTTGCATTGCTGACTTTGGGTTGGCCTTAAAGTTCGAGGCTGGCAAGTCTGCAGGTGACACCCATGGGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000052155:ENSMUST00000063886:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.058
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(16.7=100)
A:
NA
C2:
PF0006920=Pkinase=FE(13.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCTCACTGTCAGACTTTCTT
R:
ATGGGTGTCACCTGCAGACTT
Band lengths:
255-1268
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types