HsaALTA1051909-2/2 @ hg38
Alternative 3'ss
Gene
ENSG00000187045 | TMPRSS6
Description
transmembrane protease, serine 6 [Source:HGNC Symbol;Acc:HGNC:16517]
Coordinates
chr22:37084295-37084839:-
Coord C1 exon
chr22:37084727-37084839
Coord A exon
chr22:37084405-37084469
Coord C2 exon
chr22:37084295-37084404
Length
65 bp
Sequences
Splice sites
5' ss Seq
ACGGTGAGA
5' ss Score
8.94
3' ss Seq
TTCCTTCTCTTTGTTGTTAGGGA
3' ss Score
8.35
Exon sequences
Seq C1 exon
CCTGTGAAGTGAACCTGACGCTGGACAACAGGCTCGACTCCCAGGGCGTCCTCAGCACCCCGTACTTCCCCAGCTACTACTCGCCCCAAACCCACTGCTCCTGGCACCTCACG
Seq A exon
GGAGGTGGGTTCACCAACCTGGCCACACCCCATGGGCCACCTGATGGCCCGCTCCTCCCTCCCAG
Seq C2 exon
GTGCCCTCTCTGGACTACGGCTTGGCCCTCTGGTTTGATGCCTATGCACTGAGGAGGCAGAAGTATGATTTGCCGTGCACCCAGGGCCAGTGGACGATCCAGAACAGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000187045-17-19,17-18-2/2
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
ORF disruption when splice site is used (sequence inclusion)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.003
Domain overlap (PFAM):
C1:
PF0043115=CUB=PU(28.2=81.6)
A:
NA
C2:
PF0043115=CUB=PD(53.0=94.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTGAAGTGAACCTGACGCTG
R:
TACTTCTGCCTCCTCAGTGCA
Band lengths:
176-241
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains