HsaALTD0002953-2/3 @ hg19
Alternative 5'ss
Gene
ENSG00000169919 | GUSB
Description
glucuronidase, beta [Source:HGNC Symbol;Acc:4696]
Coordinates
chr7:65441002-65444464:-
Coord C1 exon
chr7:65444389-65444464
Coord A exon
chr7:65444386-65444388
Coord C2 exon
chr7:65441002-65441189
Length
3 bp
Sequences
Splice sites
5' ss Seq
GTGGTGAGG
5' ss Score
6.13
3' ss Seq
GTCTCTCTTGTTTCTTGCAGGGC
3' ss Score
11.58
Exon sequences
Seq C1 exon
CGGTCTGTACTTCTGTACACGACACCCACCACCTACATCGATGACATCACCGTCACCACCAGCGTGGAGCAAGACA
Seq A exon
GTG
Seq C2 exon
GGCTGGTGAATTACCAGATCTCTGTCAAGGGCAGTAACCTGTTCAAGTTGGAAGTGCGTCTTTTGGATGCAGAAAACAAAGTCGTGGCGAATGGGACTGGGACCCAGGGCCAACTTAAGGTGCCAGGTGTCAGCCTCTGGTGGCCGTACCTGATGCACGAACGCCCTGCCTATCTGTATTCATTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169919-9-8,10-8,11-8-2/3
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0283713=Glyco_hydro_2_N=PD(15.8=61.2),PF0070316=Glyco_hydro_2=PU(15.7=32.7)
A:
NA
C2:
PF0070316=Glyco_hydro_2=FE(73.8=100),PF0283612=Glyco_hydro_2_C=PU(0.7=3.2)
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACACCCACCACCTACATCGAT
R:
AGGTTACTGCCCTTGACAGAGA
Band lengths:
95-98
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)