HsaALTD0002953-3/3 @ hg19
Alternative 5'ss
Gene
ENSG00000169919 | GUSB
Description
glucuronidase, beta [Source:HGNC Symbol;Acc:4696]
Coordinates
chr7:65441002-65444464:-
Coord C1 exon
chr7:65444389-65444464
Coord A exon
chr7:65444373-65444388
Coord C2 exon
chr7:65441002-65441189
Length
16 bp
Sequences
Splice sites
5' ss Seq
CTGGTAGGA
5' ss Score
6.77
3' ss Seq
GTCTCTCTTGTTTCTTGCAGGGC
3' ss Score
11.58
Exon sequences
Seq C1 exon
CGGTCTGTACTTCTGTACACGACACCCACCACCTACATCGATGACATCACCGTCACCACCAGCGTGGAGCAAGACA
Seq A exon
GTGGTGAGGGCTTCTG
Seq C2 exon
GGCTGGTGAATTACCAGATCTCTGTCAAGGGCAGTAACCTGTTCAAGTTGGAAGTGCGTCTTTTGGATGCAGAAAACAAAGTCGTGGCGAATGGGACTGGGACCCAGGGCCAACTTAAGGTGCCAGGTGTCAGCCTCTGGTGGCCGTACCTGATGCACGAACGCCCTGCCTATCTGTATTCATTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169919-9-8,10-8,11-8-3/3
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
ORF disruption when splice site is used (sequence inclusion)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0283713=Glyco_hydro_2_N=PD(15.8=61.2),PF0070316=Glyco_hydro_2=PU(15.7=32.7)
A:
NA
C2:
PF0070316=Glyco_hydro_2=FE(73.8=100),PF0283612=Glyco_hydro_2_C=PU(0.7=3.2)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACACCCACCACCTACATCGAT
R:
CGCACTTCCAACTTGAACAGG
Band lengths:
113-129
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)