HsaEX0013872 @ hg19
Exon Skipping
Gene
ENSG00000117335 | CD46
Description
CD46 molecule, complement regulatory protein [Source:HGNC Symbol;Acc:6953]
Coordinates
chr1:207940358-207943707:+
Coord C1 exon
chr1:207940358-207940540
Coord A exon
chr1:207941124-207941168
Coord C2 exon
chr1:207943666-207943707
Length
45 bp
Sequences
Splice sites
3' ss Seq
ATTATTATTTTGTTTTCCAGTGT
3' ss Score
8.12
5' ss Seq
CAGGTTTAG
5' ss Score
3.14
Exon sequences
Seq C1 exon
TGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTACAAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAAAGTGTCTTAAAG
Seq A exon
TGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAG
Seq C2 exon
GTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000117335_MULTIEX1-2/3=C1-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.741 C2=0.586
Domain overlap (PFAM):
C1:
PF0008415=Sushi=WD(100=90.3),PF0200911=Rifin_STEVOR=PU(2.9=3.2)
A:
PF0248011=Herpes_gE=FE(16.3=100),PF151021=TMEM154=FE(14.4=100),PF0200911=Rifin_STEVOR=PU(21.5=87.5)
C2:
PF146101=DUF4448=FE(9.3=100)
Other Inclusion Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAGTTATGTTTGAATGCGATAAGGG
R:
TGGAGGCTTGTAAGTAGGCCT
Band lengths:
132-177
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)