HsaEX0014008 @ hg19
Exon Skipping
Gene
ENSG00000101224 | CDC25B
Description
cell division cycle 25 homolog B (S. pombe) [Source:HGNC Symbol;Acc:1726]
Coordinates
chr20:3781109-3781740:+
Coord C1 exon
chr20:3781109-3781145
Coord A exon
chr20:3781390-3781512
Coord C2 exon
chr20:3781618-3781740
Length
123 bp
Sequences
Splice sites
3' ss Seq
CGCCCTGCCTGGCTCTCTAGGTG
3' ss Score
10.58
5' ss Seq
AATGTGCGC
5' ss Score
2.86
Exon sequences
Seq C1 exon
CGAGCAGTTTGCCATCAGACGCTTCCAGTCTATGCCG
Seq A exon
GTGAGGCTGCTGGGCCACAGCCCCGTGCTTCGGAACATCACCAACTCCCAGGCGCCCGACGGCCGGAGGAAGAGCGAGGCGGGCAGTGGAGCTGCCAGCAGCTCTGGGGAAGACAAGGAGAAT
Seq C2 exon
GATGGATTTGTCTTCAAGATGCCATGGAAGCCCACACATCCCAGCTCCACCCATGCTCTGGCAGAGTGGGCCAGCCGCAGGGAAGCCTTTGCCCAGAGACCCAGCTCGGCCCCCGACCTGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000101224_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.773 C2=0.680
Domain overlap (PFAM):
C1:
PF066178=M-inducer_phosp=FE(28.6=100),PF066178=M-inducer_phosp=PU(0.1=0.0)
A:
PF066178=M-inducer_phosp=FE(14.7=100)
C2:
PF066178=M-inducer_phosp=PD(0.1=0.0),PF066178=M-inducer_phosp=FE(20.9=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGAGCAGTTTGCCATCAGACG
R:
CCGAGCTGGGTCTCTGGG
Band lengths:
146-269
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)