HsaEX0014010 @ hg19
Exon Skipping
Gene
ENSG00000101224 | CDC25B
Description
cell division cycle 25 homolog B (S. pombe) [Source:HGNC Symbol;Acc:1726]
Coordinates
chr20:3782928-3783619:+
Coord C1 exon
chr20:3782928-3783023
Coord A exon
chr20:3783377-3783455
Coord C2 exon
chr20:3783557-3783619
Length
79 bp
Sequences
Splice sites
3' ss Seq
TTTCTCTTTCCCCTTGGAAGGTT
3' ss Score
8.73
5' ss Seq
CAGGTGTGG
5' ss Score
6.34
Exon sequences
Seq C1 exon
AAAGCCCGCGTCCTCCGCTCAAAATCACTGTGTCACGATGAGATCGAGAACCTCCTGGACAGTGACCACCGAGAGCTGATTGGAGATTACTCTAAG
Seq A exon
GTTGTTCCCTGGGTGTCAGACCCAAGAGGTGCCTCTCAGTTGCCATGGGAACCAGAACTGAATTTGAAGGCCAAAGCAG
Seq C2 exon
GCCTTCCTCCTACAGACAGTAGACGGAAAGCACCAAGACCTCAAGTACATCTCACCAGAAACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000101224_CASSETTE3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.172 A=0.741 C2=0.173
Domain overlap (PFAM):
C1:
PF066178=M-inducer_phosp=PD(21.5=53.1)
A:
NO
C2:
NO
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTCCTCCGCTCAAAATCACT
R:
CGTTTCTGGTGAGATGTACTTGAGG
Band lengths:
151-230
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)