HsaEX0015637 @ hg38
Exon Skipping
Gene
ENSG00000172243 | CLEC7A
Description
C-type lectin domain family 7 member A [Source:HGNC Symbol;Acc:HGNC:14558]
Coordinates
chr12:10123245-10125448:-
Coord C1 exon
chr12:10125297-10125448
Coord A exon
chr12:10125087-10125173
Coord C2 exon
chr12:10123245-10123363
Length
87 bp
Sequences
Splice sites
3' ss Seq
TTTTTTTTTTTTTGAGGCAGAGT
3' ss Score
3.03
5' ss Seq
TAGGTAGGA
5' ss Score
7
Exon sequences
Seq C1 exon
GGGTTCTTTCCAGCCCTTGTCCTCCTAATTGGATTATATATGAGAAGAGCTGTTATCTATTCAGCATGTCACTAAATTCCTGGGATGGAAGTAAAAGACAATGCTGGCAACTGGGCTCTAATCTCCTAAAGATAGACAGCTCAAATGAATTG
Seq A exon
AGTCTCACTCTGTTGCCCAAGCTAGAGTGCAGTGAAGCCGCGACATCCCAGGCTCAAGTGATCCTCCCACCTCAGCTTCCTGAGTAG
Seq C2 exon
GGATTTATAGTAAAACAAGTGTCTTCCCAACCTGATAATTCATTTTGGATAGGCCTTTCTCGGCCCCAGACTGAGGTACCATGGCTCTGGGAGGATGGATCAACATTCTCTTCTAACTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000172243_MULTIEX1-5/6=4-6
Average complexity
C2*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.143 C2=0.000
Domain overlap (PFAM):
C1:
PF0033515=Tetraspannin=FE(35.5=100),PF083915=Ly49=PD(6.2=9.8),PF0005916=Lectin_C=PU(25.2=52.9)
A:
NO
C2:
PF0033515=Tetraspannin=PD(2.1=7.5),PF0005916=Lectin_C=FE(36.4=100)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCCAGCCCTTGTCCTCCTAA
R:
TCAGGTTGGGAAGACACTTGT
Band lengths:
180-267
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development