HsaEX0018274 @ hg38
Exon Skipping
Gene
ENSG00000138115 | CYP2C8
Description
cytochrome P450 family 2 subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:2622]
Coordinates
chr10:95042890-95058511:-
Coord C1 exon
chr10:95058335-95058511
Coord A exon
chr10:95045810-95045951
Coord C2 exon
chr10:95042890-95043077
Length
142 bp
Sequences
Splice sites
3' ss Seq
TTGCATGAAATCACTTCTAGGAA
3' ss Score
6.52
5' ss Seq
CAGGTAGGA
5' ss Score
9.79
Exon sequences
Seq C1 exon
GTCTGCAATAATTTCCCTCTACTCATTGATTGTTTCCCAGGAACTCACAACAAAGTGCTTAAAAATGTTGCTCTTACACGAAGTTACATTAGGGAGAAAGTAAAAGAACACCAAGCATCACTGGATGTTAACAATCCTCGGGACTTTATCGATTGCTTCCTGATCAAAATGGAGCAG
Seq A exon
GAAAAGGACAACCAAAAGTCAGAATTCAATATTGAAAACTTGGTTGGCACTGTAGCTGATCTATTTGTTGCTGGAACAGAGACAACAAGCACCACTCTGAGATATGGACTCCTGCTCCTGCTGAAGCACCCAGAGGTCACAG
Seq C2 exon
CTAAAGTCCAGGAAGAGATTGATCATGTAATTGGCAGACACAGGAGCCCCTGCATGCAGGATAGGAGCCACATGCCTTACACTGATGCTGTAGTGCACGAGATCCAGAGATACAGTGACCTTGTCCCCACCGGTGTGCCCCATGCAGTGACCACTGATACTAAGTTCAGAAACTACCTCATCCCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138115_CASSETTE2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.098
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(12.7=100)
A:
PF0006717=p450=FE(10.3=100)
C2:
PF0006717=p450=FE(13.5=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGGAACTCACAACAAAGTGC
R:
CTGGATCTCGTGCACTACAGC
Band lengths:
248-390
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development