HsaEX0019108 @ hg19
Exon Skipping
Gene
ENSG00000213047 | DENND1B
Description
DENN/MADD domain containing 1B [Source:HGNC Symbol;Acc:28404]
Coordinates
chr1:197564338-197576304:-
Coord C1 exon
chr1:197576203-197576304
Coord A exon
chr1:197564875-197564897
Coord C2 exon
chr1:197564338-197564463
Length
23 bp
Sequences
Splice sites
3' ss Seq
AAATTATATATGCAAATGAGACT
3' ss Score
-11.87
5' ss Seq
ATGGTAAGT
5' ss Score
11.01
Exon sequences
Seq C1 exon
AGAGTGAAAAACAAATCATTGGAAGATGTTGTTATGTTAAATGTTGATACAAACACATTAGAATCACCATTTAGTGACTTGAACAACCTACCAAGTGATGTG
Seq A exon
ACTTCCAAAAATAAAATTAAATG
Seq C2 exon
GTCTCGGCCTTGAAAAATAAACTGAAGAAGCAGTCTACAGCTACGGGTGATGGAGTAGCTAGGGCCTTTCTTAGAGCACAGGCTGCTTTGTTTGGATCCTACAGAGATGCACTGAGATACAAACCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000213047-'24-26,'24-25,26-26
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0214116=DENN=PD(9.4=50.0)
A:
NO
C2:
PF0345514=dDENN=PU(40.3=64.3)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGACTTGAACAACCTACCAAGTGA
R:
GCCTGTGCTCTAAGAAAGGCC
Band lengths:
111-134
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)