HsaEX0019148 @ hg19
Exon Skipping
Gene
ENSG00000162777 | DENND2D
Description
DENN/MADD domain containing 2D [Source:HGNC Symbol;Acc:26192]
Coordinates
chr1:111737200-111738678:-
Coord C1 exon
chr1:111738538-111738678
Coord A exon
chr1:111738290-111738450
Coord C2 exon
chr1:111737200-111737348
Length
161 bp
Sequences
Splice sites
3' ss Seq
ACTGTTCTTCCATTAACCAGGTT
3' ss Score
7.67
5' ss Seq
CATGTAAGT
5' ss Score
8.31
Exon sequences
Seq C1 exon
ATCCTGGATGAAGTGGAGAAGAGACATCAGATCTCCATGGCTGTCATCTACCCGTTCATGCAGGGCCTCCGAGAGGCAGCCTTCCCTGCTCCTGGGAAGACTGTCACTCTCAAGAGCTTCATCCCCGACTCAGGCACTGAG
Seq A exon
GTTAAAGTACAGAGAAACTGAGCCAGATGGGGACTGGGACTTGGTTAGAATGGACAAAGCTGAAATCAAACCCAGATTTTCTGATCCTTCTAACTTGATACCCACAAGCACCTAGTTACTGCTCAAGCCACCAAGACTTTTATTTATAATAAATAAACCAT
Seq C2 exon
TTCATTTCACTGACACGGCCCCTGGACTCCCACCTAGAACATGTGGATTTTAGTTCTCTATTGCACTGTCTCAGTTTTGAACAGATACTTCAGATCTTTGCCTCTGCCGTGCTGGAGAGAAAAATCATCTTCCTGGCGGAAGGTCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162777_MULTIEX1-5/8=4-6
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.333 C2=0.000
Domain overlap (PFAM):
C1:
PF0214116=DENN=FE(24.9=100)
A:
PF0214116=DENN=PD(5.6=57.1)
C2:
PF0214116=DENN=FE(26.5=100)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCTGTCATCTACCCGTTCA
R:
CTGAGACCTTCCGCCAGGA
Band lengths:
253-414
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)