HsaEX0019935 @ hg19
Exon Skipping
Gene
ENSG00000144355 | DLX1
Description
distal-less homeobox 1 [Source:HGNC Symbol;Acc:2914]
Coordinates
chr2:172949469-172954405:+
Coord C1 exon
chr2:172949469-172949609
Coord A exon
chr2:172950040-172950718
Coord C2 exon
chr2:172952731-172954405
Length
679 bp
Sequences
Splice sites
3' ss Seq
CCCGGCGCGCTCTGTTGCAGAGG
3' ss Score
7.93
5' ss Seq
CAGGTACGT
5' ss Score
10.65
Exon sequences
Seq C1 exon
GGAGGAGAAGCGCGGGTTCCTGGCTCTCCACGCGCACTGCTTTAATCAGACCCGTGCAGCCTCGAGCTGGAGTGGCCAGCTGGGCCTGGAGCAATGCGAGCGGGCCCCAGGGAGCGACAGCGGCGTTGGCGCAGCGGCCGA
Seq A exon
AGGAGCCCCGGCCGGGAAGTGTGGATGCGTCTTACCCGAGGCCGGGCCGCCTCGCCCGCTCTAGTCCAGCGGAGCCCGAGCGCCTCGGACCAATCCCCAGTGATTATGCAAGACAGCGGACCAATCAGCTCCGCCAGCTCATGAATATTTATGACCTTCGCTGAGTCAAAGCTTTGAACCGAGTTTGGGGAGCTCAGCAGCATCATGCTTAGACTTTTCAAAGAGACAAACTCCATTTTCTTATGAATGGAAAGTGAAAACCCCTGTTCCGCTTAAATTGGGTTCCTTCCTGTCCTGAGAAACATAGAGACCCCCAAAAGGGAAGCAGAGGAGAGAAAGTCCCACACCCAGACCCCGCGAGAAGAGATGACCATGACCACCATGCCAGAAAGTCTCAACAGCCCCGTGTCGGGCAAGGCGGTGTTTATGGAGTTTGGGCCGCCCAACCAGCAAATGTCTCCTTCTCCCATGTCCCACGGGCACTACTCCATGCACTGTTTACACTCGGCGGGCCATTCGCAGCCCGACGGCGCCTACAGCTCAGCCTCGTCCTTCTCCCGACCGCTGGGCTACCCCTACGTCAACTCGGTCAGCAGCCACGCATCCAGCCCCTACATCAGTTCGGTGCAGTCCTACCCGGGCAGCGCCAGCCTCGCCCAGAGCCGCCTGGAGGACCCAG
Seq C2 exon
GTCAAGATCTGGTTCCAAAACAAGCGATCCAAGTTCAAGAAGCTGATGAAGCAGGGTGGGGCGGCTCTGGAGGGTAGTGCGTTGGCCAACGGTCGGGCCCTGTCTGCTGGCTCCCCACCCGTGCCGCCCGGCTGGAACCCTAACTCTTCATCCGGGAAGGGCTCAGGAGGAAACGCGGGCTCCTATATCCCCAGCTACACATCGTGGTACCCTTCAGCGCACCAAGAAGCTATGCAGCAACCCCAACTTATGTGAGGTTGCCCGCCCGTCTCCTTCTTGTCTCCCCGGCCCAGGTCCCTCCCGCCTCCAGGTCCATCCATCCCGTCCGGAAAAGAAGGACCCAGAGGGAAGAAGGAACAGTGGAGGCGGGACGCCCTCCATCTCCTCGGAGCCCCGCGAGGTCCGGCCCAGCAACTTCCCGGCATCCGCGCTCTAGCCTGAACCCTGGCCTGGGCCGAGCAGTGGCAGCAGAGAGTGGCCTCGGAGGGAAGCCACTGCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144355_MULTIEX1-1/2=C1-C2
Average complexity
C3*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.614 C2=0.567
Domain overlap (PFAM):
C1:
NA
A:
NO
C2:
PF0004624=Homeobox=PD(22.8=15.3)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGCGCACTGCTTTAATCAGA
R:
CATAGCTTCTTGGTGCGCTGA
Band lengths:
346-1025
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)