HsaEX0030099 @ hg19
Exon Skipping
Gene
ENSG00000204525 | HLA-C
Description
major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:4933]
Coordinates
chr6:31237270-31238199:-
Coord C1 exon
chr6:31237987-31238199
Coord A exon
chr6:31237743-31237862
Coord C2 exon
chr6:31237270-31237302
Length
120 bp
Sequences
Splice sites
3' ss Seq
ACCTTCTCCTCCTTTCCCAGAGC
3' ss Score
10.77
5' ss Seq
CAGGTAGGG
5' ss Score
9.46
Exon sequences
Seq C1 exon
GGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGGCAGCGGGATGGGGAGGACCAGACCCAGGACACCGAGCTTGTGGAGACCAGGCCAGCAGGAGATGGAACCTTCCAGAAGTGGGCAGCTGTGGTGGTGCCTTCTGGACAAGAGCAGAGATACACGTGCCATATGCAGCACGAGGGGCTGCAAGAGCCCCTCACCCTGAGCTGGG
Seq A exon
AGCCATCTTCCCAGCCCACCATCCCCATCATGGGCATCGTTGCTGGCCTGGCTGTCCTGGTTGTCCTAGCTGTCCTTGGAGCTGTGGTCACCGCTATGATGTGTAGGAGGAAGAGCTCAG
Seq C2 exon
GTGGAAAAGGAGGGAGCTGCTCTCAGGCTGCGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204525-'8-10,'8-7,9-10
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.387 A=0.000 C2=0.074
Domain overlap (PFAM):
C1:
PF0765410=C1-set=WD(100=93.5)
A:
PF126692=P12=PU(53.6=73.2),PF066236=MHC_I_C=PU(6.9=4.9)
C2:
PF126692=P12=FE(27.4=100),PF066236=MHC_I_C=PU(44.8=72.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTTCTACCCTGCGGAGATCA
R:
CAGCCTGAGAGCAGCTCCC
Band lengths:
234-354
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)