HsaEX0032434 @ hg19
Exon Skipping
Gene
ENSG00000150093 | ITGB1
Description
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) [Source:HGNC Symbol;Acc:6153]
Coordinates
chr10:33221443-33224486:-
Coord C1 exon
chr10:33224420-33224486
Coord A exon
chr10:33222279-33222511
Coord C2 exon
chr10:33221443-33221528
Length
233 bp
Sequences
Splice sites
3' ss Seq
TGCTCTTGTGTGTTTTCCAGATT
3' ss Score
11.14
5' ss Seq
CTTGTGAGT
5' ss Score
7.15
Exon sequences
Seq C1 exon
ATGAATTTACAACCAATTTTCTGGATTGGACTGATCAGTTCAGTTTGCTGTGTGTTTGCTCAAACAG
Seq A exon
ATTTTCTATAAGAAGCATATGCTGGTTTTATAATCTCAGAAAAGATACGTTGGAGACAGTCTGTATTAGCGCTTACCATGTAGAAGGCATACTCTTCCTTAGGTAGATGCAAAGAAACCTAAAACATACTTTGAACATAGAGCCTGAGAAATTCTGGGATTATGGATTAGATGAATATGGACTTTTCAGTTATTTAACATACTGAAAGCAAAGGGAAAGCCTTGAAGATTCTT
Seq C2 exon
ATGAAAATAGATGTTTAAAAGCAAATGCCAAATCATGTGGAGAATGTATACAAGCAGGGCCAAATTGTGGGTGGTGCACAAATTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000150093_CASSETTE2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0143720=PSI=PU(12.3=34.8)
A:
NO
C2:
PF0143720=PSI=PU(46.3=86.2),PF0036213=Integrin_beta=PU(15.5=58.6)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAATTTTCTGGATTGGACTGATCAGT
R:
TGAATTTGTGCACCACCCACA
Band lengths:
140-373
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)