HsaEX0035094 @ hg38
Exon Skipping
Gene
ENSG00000115919 | KYNU
Description
kynureninase [Source:HGNC Symbol;Acc:HGNC:6469]
Coordinates
chr2:143033236-143040658:+
Coord C1 exon
chr2:143033236-143033321
Coord A exon
chr2:143037136-143037273
Coord C2 exon
chr2:143040428-143040658
Length
138 bp
Sequences
Splice sites
3' ss Seq
CTGAATCATTTATACAATAGTTC
3' ss Score
2.21
5' ss Seq
AAAGTAAGA
5' ss Score
6.91
Exon sequences
Seq C1 exon
AACTGCAGTTAATCCCTGGGGTCTGTGGATTCCGAATTTCAAATCCTCCCATTTTGTTGGTCTGTTCCTTGCATGCTAGTTTAGAG
Seq A exon
TTCTTAAAATATTGTGGATCAAGGGATGAAGCCTGAGGCCAGGAACCTGGTGGCAAGTACTCTCTCCCTCAATGGACACGAAGTGTGACCTTACACAAGCAACAACTCCCTTTGGATGTATTTGCCTTATTTTTTAAA
Seq C2 exon
ATCTTTAAGCAAGCGACAATGAAGGCATTGCGGAAAAAATCTGTTTTGCTAACTGGCTATCTGGAATACCTGATCAAGCATAACTATGGCAAAGATAAAGCAGCAACCAAGAAACCAGTTGTGAACATAATTACTCCGTCTCATGTAGAGGAGCGGGGGTGCCAGCTAACAATAACATTTTCTGTTCCAAACAAAGATGTTTTCCAAGAACTAGAAAAAAGAGGAGTGGTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115919_MULTIEX2-4/5=3-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0026614=Aminotran_5=PD(9.7=93.1)
A:
PF0026614=Aminotran_5=PD(2.8=66.7)
C2:
PF0026614=Aminotran_5=PD(16.9=74.0)
Main Inclusion Isoform:
ENST00000409512fB3784
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATCCCTGGGGTCTGTGGATT
R:
TTATTGTTAGCTGGCACCCCC
Band lengths:
251-389
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development