HsaEX0035099 @ hg38
Exon Skipping
Gene
ENSG00000115919 | KYNU
Description
kynureninase [Source:HGNC Symbol;Acc:HGNC:6469]
Coordinates
chr2:142985948-143040658:+
Coord C1 exon
chr2:142985948-142986021
Coord A exon
chr2:143033236-143033321
Coord C2 exon
chr2:143040428-143040658
Length
86 bp
Sequences
Splice sites
3' ss Seq
ACATGATATTAATTTCTCAGAAC
3' ss Score
5.85
5' ss Seq
GAGGTAAGT
5' ss Score
11.08
Exon sequences
Seq C1 exon
TATTTAAATGCAGGAGCAGGAGGAATTGCTGGTGCCTTCATTCATGAAAAGCATGCCCATACGATTAAACCTGC
Seq A exon
AACTGCAGTTAATCCCTGGGGTCTGTGGATTCCGAATTTCAAATCCTCCCATTTTGTTGGTCTGTTCCTTGCATGCTAGTTTAGAG
Seq C2 exon
ATCTTTAAGCAAGCGACAATGAAGGCATTGCGGAAAAAATCTGTTTTGCTAACTGGCTATCTGGAATACCTGATCAAGCATAACTATGGCAAAGATAAAGCAGCAACCAAGAAACCAGTTGTGAACATAATTACTCCGTCTCATGTAGAGGAGCGGGGGTGCCAGCTAACAATAACATTTTCTGTTCCAAACAAAGATGTTTTCCAAGAACTAGAAAAAAGAGGAGTGGTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115919_MULTIEX2-3/5=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0026614=Aminotran_5=FE(10.2=100)
A:
PF0026614=Aminotran_5=PD(9.7=93.1)
C2:
PF0026614=Aminotran_5=PD(16.9=74.0)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGGAATTGCTGGTGCCTTCA
R:
ACTGGTTTCTTGGTTGCTGCT
Band lengths:
174-260
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development