HsaEX0035436 @ hg38
Exon Skipping
Gene
ENSG00000090661 | CERS4
Description
ceramide synthase 4 [Source:HGNC Symbol;Acc:HGNC:23747]
Coordinates
chr19:8256949-8261844:+
Coord C1 exon
chr19:8256949-8257077
Coord A exon
chr19:8257879-8257985
Coord C2 exon
chr19:8261688-8261844
Length
107 bp
Sequences
Splice sites
3' ss Seq
CTCCCTGCTGCCCTTTCCAGGCC
3' ss Score
11.12
5' ss Seq
CCAGTGAGT
5' ss Score
8.28
Exon sequences
Seq C1 exon
GATTTCAAGGAGCAGGTGATACACCACTTCGTGGCGGTCATCCTGATGACCTTCTCCTACAGTGCCAACCTGCTGCGCATTGGCTCTCTGGTGCTGCTGTTACACGATTCCTCTGACTACCTGCTGGAG
Seq A exon
GCCTGTAAGATGGTCAACTACATGCAGTATCAGCAAGTGTGCGACGCTCTCTTCCTCATCTTCTCCTTTGTCTTCTTCTACACCCGACTGGTCCTCTTTCCCACCCA
Seq C2 exon
GATCCTCTACACCACATACTACGAGTCCATCAGCAACAGGGGCCCCTTCTTCGGCTACTACTTCTTCAACGGGCTTCTGATGTTGCTGCAGCTGCTGCACGTGTTCTGGTCTTGCCTCATTCTGCGCATGCTCTATAGCTTCATGAAGAAGGGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000090661_MULTIEX2-3/5=2-5
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0379811=TRAM_LAG1_CLN8=FE(21.6=100)
A:
PF0379811=TRAM_LAG1_CLN8=FE(18.0=100)
C2:
PF0379811=TRAM_LAG1_CLN8=PD(21.6=79.2)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCAAGGAGCAGGTGATACAC
R:
ATGAGGCAAGACCAGAACACG
Band lengths:
246-353
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development