HsaEX0036935 @ hg19
Exon Skipping
Gene
ENSG00000168056 | LTBP3
Description
latent transforming growth factor beta binding protein 3 [Source:HGNC Symbol;Acc:6716]
Coordinates
chr11:65307191-65307853:-
Coord C1 exon
chr11:65307716-65307853
Coord A exon
chr11:65307484-65307624
Coord C2 exon
chr11:65307191-65307352
Length
141 bp
Sequences
Splice sites
3' ss Seq
CACCCCCTCGCTGTTCGTAGACG
3' ss Score
8.44
5' ss Seq
CCGGTGAGG
5' ss Score
9.35
Exon sequences
Seq C1 exon
ACGTGGACGAGTGCCTGGACGAGTCCAACTGCCGGAACGGAGTGTGTGAGAACACGCGCGGCGGCTACCGCTGTGCCTGCACGCCCCCTGCCGAGTACAGTCCCGCGCAGCGCCAGTGCCTGAGCCCGGAAGAGATGG
Seq A exon
ACGTGGACGAGTGCCAGGACCCGGCAGCCTGCCGCCCTGGCCGCTGCGTCAACCTGCCGGGCTCCTACCGCTGCGAGTGTCGCCCGCCCTGGGTGCCCGGGCCCTCCGGCCGCGATTGCCAGCTCCCCGAGAGCCCGGCCG
Seq C2 exon
AGCGTGCCCCGGAGCGGCGCGACGTGTGCTGGAGCCAGCGCGGAGAGGACGGCATGTGCGCTGGCCCCCTGGCCGGGCCTGCCCTCACCTTCGACGACTGCTGCTGCCGCCAGGGCCGCGGCTGGGGCGCCCAATGCCGACCGTGCCCGCCGCGCGGCGCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168056_MULTIEX1-2/2=1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show structural model
Features
Disorder rate (Iupred):
C1=0.028 A=0.188 C2=0.055
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=85.1),PF106004=PDZ_assoc=PU(89.1=87.2)
A:
PF0764510=EGF_CA=WD(100=83.3)
C2:
PF106004=PDZ_assoc=PD(8.7=7.3),PF0068312=TB=PU(82.2=67.3)
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTGGACGAGTGCCTGGA
R:
CAGCAGCAGTCGTCGAAGG
Band lengths:
243-384
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)