HsaEX0037478 @ hg38
Exon Skipping
Gene
ENSG00000034152 | MAP2K3
Description
mitogen-activated protein kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6843]
Coordinates
chr17:21284672-21298479:+
Coord C1 exon
chr17:21284672-21284969
Coord A exon
chr17:21296086-21296210
Coord C2 exon
chr17:21298413-21298479
Length
125 bp
Sequences
Splice sites
3' ss Seq
TTTTTTTTTCACCTCTGCAGAGA
3' ss Score
10.71
5' ss Seq
CAGGTGGGT
5' ss Score
8.56
Exon sequences
Seq C1 exon
AGTCAGCGCAGTTCGGCCGGGGTCTCCCCGGCGCTGCCCAGTCTGTCTCCGGCGCCGCCCGTCGCGGACTCGTCCTTGCTGCAGTCGCCGCCGCAGTCCTCGCCGCAGTCGCCGCCGCCGCCGCCGCCGCCGCCGCTGCTCCTCCGCCTGGCCTGGGCCGTCTGCCCGCAGCCATGAGCGTGCTCGGCCCCGGTGGAGCCCGCAGTCCTCTAGATTAGTCTCCACCGCCGTCCAGGACCCACTTGCAGCATGGAGTCGCCCGCCTCGAGCCAGCCCGCCAGCATGCCCCAGTCCAAAG
Seq A exon
AGAGGCTGGTCATATCCATGGTGACCATTTATGGGCCACAACAGGTCCCCATCTGCGCAGTGAACCCTGTGCTGAGCACCTTGCAGACGTGATCTTGCTTCGTCCTGCAGCACTGTGCGGGGCAG
Seq C2 exon
GAAAATCCAAGAGGAAGAAGGATCTACGGATATCCTGCATGTCCAAGCCACCCGCACCCAACCCCAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000034152_MULTIEX2-4/4=C1-C2
Average complexity
ME(1-4[98=100];2-4[99=100])
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.921 A=0.090 C2=1.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCGTCCTTGCTGCAGTCG
R:
CGTAGATCCTTCTTCCTCTTGGA
Band lengths:
258-383
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development