HsaEX0039540 @ hg19
Exon Skipping
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 [Source:HGNC Symbol;Acc:16063]
Coordinates
chr10:21827762-21875277:+
Coord C1 exon
chr10:21827762-21827841
Coord A exon
chr10:21846550-21846753
Coord C2 exon
chr10:21875223-21875277
Length
204 bp
Sequences
Splice sites
3' ss Seq
TTCATTCTCTCATACTACAGACT
3' ss Score
6.93
5' ss Seq
GGGGTAAGA
5' ss Score
7.83
Exon sequences
Seq C1 exon
CTTGCTATGGCATTGTTCAAGTACCCACTGGACCGTGGTTTTGCAGGAAATGTGAATCTCAGGAGAGAGCAGCCAGAGTG
Seq A exon
ACTCTACTTCATGAGGCTGGAACCATGACTGCTGGCAGCTCTTGTTTCCAGCCCCTTTTACCAGAAGAAGGGGCTCTCTAGAAGAATCCTGGAAAGGACTCTGATTGGCCTGTCTTGGATCATGTGCCCATCATCTCTGTGGCTGGAGTGGGGAGGGTACTGTGAATGGCAACCCTCACTAGAACTACATAGTTGGAGTCAGGG
Seq C2 exon
AGATGTGAACTTTGTCCCCATAAGGATGGAGCTTTAAAAAGAACAGATAATGGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403_MULTIEX1-4/8=2-6
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF138311=PHD_2=PD(48.6=66.7),PF138321=zf-HC5HC2H_2=PU(0.1=0.0)
A:
NO
C2:
PF138321=zf-HC5HC2H_2=FE(15.3=100)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTATGGCATTGTTCAAGTACCC
R:
CCCCATTATCTGTTCTTTTTAAAGCT
Band lengths:
132-336
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)