Special

MmuEX0029212 @ mm9

Exon Skipping

Gene
Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 [Source:MGI Symbol;Acc:MGI:1329038]
Coordinates
chr2:17992752-18031518:+
Coord C1 exon
chr2:17992752-17992831
Coord A exon
chr2:18004138-18004352
Coord C2 exon
chr2:18031409-18031518
Length
215 bp
Sequences
Splice sites
3' ss Seq
TTCATTCTCTTATACTACAGACT
3' ss Score
7.04
5' ss Seq
GGGGTAAGA
5' ss Score
7.83
Exon sequences
Seq C1 exon
CTTGCTATGGCATTGTTCAAGTACCTACTGGACCGTGGTTTTGTAGGAAATGTGAATCTCAGGAGAGAGCAGCCAGAGTG
Seq A exon
ACTCTCTACTACATGAGGCTGGAACCATGACTGCTGGCAGCTCTTGGCTTTCATCTTCCCAGCCCCTTCTACCAGGAAAAGGGGCTCTTTTGAAGAATCCTGAGAAGGACTCTGATTGACCTGTCTTGGATCATGTACCCATCATCCCTCTGGCTGGAGTGGGGAGGGCTCTATGAATTGCAACCCTCACTAGAACTACATAGTTGGAGTCAGGG
Seq C2 exon
GTTGGGCTCATGTGGTTTGTGCCCTCTATATTCCAGAGGTACAATTTGCCAATGTTTCTACAATGGAGCCAATCGTTTTACAGTCTGTCCCACATGATCGTTATAATAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026743_MULTIEX1-1/18=C1-5
Average complexity
C3*
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence inclusion

Show structural model
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF138311=PHD_2=PD(48.6=66.7),PF138321=zf-HC5HC2H_2=PU(0.1=0.0)
A:
NO
C2:
PF138321=zf-HC5HC2H_2=FE(30.5=100)


Main Inclusion Isoform:


Main Skipping Isoform:


Other Inclusion Isoforms:
NA
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCTATGGCATTGTTCAAGTACCT
R:
CTTATTATAACGATCATGTGGGACAG
Band lengths:
188-403
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types