HsaEX0042215 @ hg19
Exon Skipping
Gene
ENSG00000166579 | NDEL1
Description
nudE nuclear distribution E homolog (A. nidulans)-like 1 [Source:HGNC Symbol;Acc:17620]
Coordinates
chr17:8347578-8349182:+
Coord C1 exon
chr17:8347578-8347675
Coord A exon
chr17:8348272-8348358
Coord C2 exon
chr17:8349029-8349182
Length
87 bp
Sequences
Splice sites
3' ss Seq
TTTCCTATTTTGGTTAACAGAGT
3' ss Score
7.28
5' ss Seq
AAGGTGTGT
5' ss Score
6.64
Exon sequences
Seq C1 exon
GCTTTCTTGATCATGGATGGTGAAGATATACCAGATTTTTCAAGTTTAAAGGAGGAAACTGCTTATTGGAAGGAACTTTCCTTGAAGTATAAGCAAAG
Seq A exon
AGTTTACTAAGTCTTATCAAACCTTTTACTGCCCTTTCATTATTATCACCGAAGTCAGTTATTCTATTGTGCCAGTGGATATGAAAG
Seq C2 exon
CTTCCAGGAAGCTCGGGATGAGCTAGTTGAATTCCAGGAAGGAAGCAGAGAATTAGAAGCAGAGTTGGAGGCACAATTAGTACAGGCTGAACAAAGAAATAGAGACTTGCAGGCTGATAACCAAAGACTGAAATATGAAGTGGAGGCATTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166579_MULTIEX1-1/2=C1-2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.132 A=0.000 C2=0.108
Domain overlap (PFAM):
C1:
PF079267=TPR_MLP1_2=PU(34.2=93.1),PF152721=BBP1_C=PU(12.1=58.6),PF102414=KxDL=PU(10.0=24.1),PF104734=CENP-F_leu_zip=PU(7.2=34.5)
A:
NO
C2:
PF079267=TPR_MLP1_2=FE(64.6=100),PF152721=BBP1_C=FE(37.2=100),PF104734=CENP-F_leu_zip=FE(39.8=100),PF102414=KxDL=FE(72.9=100),PF138701=DUF4201=PU(34.4=59.6),PF0218313=HALZ=PU(75.0=40.4)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTTTCTTGATCATGGATGGTGA
R:
TTGTGCCTCCAACTCTGCTTC
Band lengths:
174-261
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)