HsaEX0045759 @ hg19
Exon Skipping
Gene
ENSG00000105717 | PBX4
Description
pre-B-cell leukemia homeobox 4 [Source:HGNC Symbol;Acc:13403]
Coordinates
chr19:19710101-19729725:-
Coord C1 exon
chr19:19729320-19729725
Coord A exon
chr19:19717691-19717792
Coord C2 exon
chr19:19710101-19710174
Length
102 bp
Sequences
Splice sites
3' ss Seq
GTTTGTTTGTTTTGAGACAGAGT
3' ss Score
1.15
5' ss Seq
CAGGTAGCT
5' ss Score
6.52
Exon sequences
Seq C1 exon
AGAAGTGCCGTTGCCTCGGCAACCCCAAACCCAGTCCAAGCCCGGAGAGGGGGAAGTTCGGGGCGAGTCCCGGGGGCGGTGCGTGGCGCCGGTTGGCTGACGGAGATGAAGGGGCGTGTCTGTAGGCGGTGCAATACACGGGTTGGCTGGCGATAGCGGCGGTGGGCGTGGCTTAGGCGCGAGCGAGAGCGGGCGCGGCGCTCAGGCAGCGGCGGTTGGCTGCGGCGCCAGTGGTAGTGCTCCAGGCTCGACGGCACCCTCACAGCGCCCGCCCGGCCCTGCCGCTCATGGCCGCCCCGCCGCGCCCCGCGCCATCGCCCCCCGCCCCGCGGCGCCTCGACACGAGCGACGTCCTGCAGCAGATCATGGCCATCACCGACCAGAGCCTGGACGAGGCACAGGCCAG
Seq A exon
AGTCTTGCTGTGTCACCCAGCCTGGAGTTCAGTGGCGCGATCTTGGCTCACTGCAACCTTCACCTCCTGGTTTCAAGTGATTGTCATGCCTCAGCCTCCCAG
Seq C2 exon
AAAGCATGCTCTGAATTGCCATCGGATGAAGCCTGCTCTGTTCAGCGTGCTCTGTGAGATCAAGGAAAAGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105717-'0-1,'0-0,1-1
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.700 A=0.000 C2=0.115
Domain overlap (PFAM):
C1:
PF037928=PBC=PU(14.1=70.0)
A:
PF037928=PBC=PD(31.0=37.1),PF037928=PBC=PU(2.3=11.4)
C2:
PF037928=PBC=FE(12.6=100)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTGGTAGTGCTCCAGGCTC
R:
CCTTGATCTCACAGAGCACGC
Band lengths:
242-344
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)