HsaEX0045761 @ hg19
Exon Skipping
Gene
ENSG00000105717 | PBX4
Description
pre-B-cell leukemia homeobox 4 [Source:HGNC Symbol;Acc:13403]
Coordinates
chr19:19681395-19729725:-
Coord C1 exon
chr19:19729320-19729725
Coord A exon
chr19:19710101-19710174
Coord C2 exon
chr19:19681395-19681642
Length
74 bp
Sequences
Splice sites
3' ss Seq
CTCTGTCACCTCCCTTTCAGAAA
3' ss Score
10.22
5' ss Seq
CAGGTAGGC
5' ss Score
9.88
Exon sequences
Seq C1 exon
AGAAGTGCCGTTGCCTCGGCAACCCCAAACCCAGTCCAAGCCCGGAGAGGGGGAAGTTCGGGGCGAGTCCCGGGGGCGGTGCGTGGCGCCGGTTGGCTGACGGAGATGAAGGGGCGTGTCTGTAGGCGGTGCAATACACGGGTTGGCTGGCGATAGCGGCGGTGGGCGTGGCTTAGGCGCGAGCGAGAGCGGGCGCGGCGCTCAGGCAGCGGCGGTTGGCTGCGGCGCCAGTGGTAGTGCTCCAGGCTCGACGGCACCCTCACAGCGCCCGCCCGGCCCTGCCGCTCATGGCCGCCCCGCCGCGCCCCGCGCCATCGCCCCCCGCCCCGCGGCGCCTCGACACGAGCGACGTCCTGCAGCAGATCATGGCCATCACCGACCAGAGCCTGGACGAGGCACAGGCCAG
Seq A exon
AAAGCATGCTCTGAATTGCCATCGGATGAAGCCTGCTCTGTTCAGCGTGCTCTGTGAGATCAAGGAAAAGACAG
Seq C2 exon
TGGTAAGCATCCGTGGCATTCAAGACGAAGATCCCCCTGACGCCCAGCTCCTGAGGCTGGATAACATGCTGCTGGCTGAGGGCGTGTGCAGGCCCGAGAAGAGAGGAAGAGGAGGAGCGGTGGCCAGGGCCGGCACAGCAACACCAGGTGGCTGTCCAAATGACAATAGCATTGAGCACTCTGACTACAGGGCCAAGCTGTCCCAGATCCGACAGATTTACCACTCTGAGCTAGAGAAATATGAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105717_MULTIEX1-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.700 A=0.115 C2=0.398
Domain overlap (PFAM):
C1:
PF037928=PBC=PU(14.1=70.0)
A:
PF037928=PBC=FE(12.6=100)
C2:
PF037928=PBC=FE(41.4=100),PF0076914=ERM=PU(18.6=36.1),PF070286=DUF1319=PU(35.2=37.3),PF040917=Sec15=PU(34.1=33.7),PF0044324=UCH=PU(25.0=73.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACGTCCTGCAGCAGATCATG
R:
CGCTCCTCCTCTTCCTCTCTT
Band lengths:
178-252
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)