HsaEX0045761 @ hg38
Exon Skipping
Gene
ENSG00000105717 | PBX4
Description
PBX homeobox 4 [Source:HGNC Symbol;Acc:HGNC:13403]
Coordinates
chr19:19570586-19618916:-
Coord C1 exon
chr19:19618511-19618916
Coord A exon
chr19:19599292-19599365
Coord C2 exon
chr19:19570586-19570833
Length
74 bp
Sequences
Splice sites
3' ss Seq
CTCTGTCACCTCCCTTTCAGAAA
3' ss Score
10.22
5' ss Seq
CAGGTAGGC
5' ss Score
9.88
Exon sequences
Seq C1 exon
AGAAGTGCCGTTGCCTCGGCAACCCCAAACCCAGTCCAAGCCCGGAGAGGGGGAAGTTCGGGGCGAGTCCCGGGGGCGGTGCGTGGCGCCGGTTGGCTGACGGAGATGAAGGGGCGTGTCTGTAGGCGGTGCAATACACGGGTTGGCTGGCGATAGCGGCGGTGGGCGTGGCTTAGGCGCGAGCGAGAGCGGGCGCGGCGCTCAGGCAGCGGCGGTTGGCTGCGGCGCCAGTGGTAGTGCTCCAGGCTCGACGGCACCCTCACAGCGCCCGCCCGGCCCTGCCGCTCATGGCCGCCCCGCCGCGCCCCGCGCCATCGCCCCCCGCCCCGCGGCGCCTCGACACGAGCGACGTCCTGCAGCAGATCATGGCCATCACCGACCAGAGCCTGGACGAGGCACAGGCCAG
Seq A exon
AAAGCATGCTCTGAATTGCCATCGGATGAAGCCTGCTCTGTTCAGCGTGCTCTGTGAGATCAAGGAAAAGACAG
Seq C2 exon
TGGTAAGCATCCGTGGCATTCAAGACGAAGATCCCCCTGACGCCCAGCTCCTGAGGCTGGATAACATGCTGCTGGCTGAGGGCGTGTGCAGGCCCGAGAAGAGAGGAAGAGGAGGAGCGGTGGCCAGGGCCGGCACAGCAACACCAGGTGGCTGTCCAAATGACAATAGCATTGAGCACTCTGACTACAGGGCCAAGCTGTCCCAGATCCGACAGATTTACCACTCTGAGCTAGAGAAATATGAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105717_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.930 A=0.179 C2=0.516
Domain overlap (PFAM):
C1:
PF037928=PBC=PU(14.1=70.0)
A:
PF037928=PBC=FE(12.6=100)
C2:
PF037928=PBC=FE(41.4=100),PF070286=DUF1319=PU(35.2=37.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACGTCCTGCAGCAGATCATG
R:
CGCTCCTCCTCTTCCTCTCTT
Band lengths:
178-252
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development