HsaEX0046170 @ hg19
Exon Skipping
Gene
ENSG00000112541 | PDE10A
Description
phosphodiesterase 10A [Source:HGNC Symbol;Acc:8772]
Coordinates
chr6:165956928-166075584:-
Coord C1 exon
chr6:166075435-166075584
Coord A exon
chr6:165989900-165990027
Coord C2 exon
chr6:165956928-165957056
Length
128 bp
Sequences
Splice sites
3' ss Seq
TTTGTTTTGTTTTTGTTTAGAAG
3' ss Score
7.37
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
GCGGCGGCGGCCAAACTCCGCGGCGTCCCCAGGGCGCCAGCTTCGCCCTCGCCGCCGCGGCCGCGCTGCTCTTCGGCTCCGACATGGAAGATGGACCTTCTAATAATGCGAGCTGCTTCCGAAGGCTGACCGAGTGCTTCCTGAGCCCCA
Seq A exon
AAGCTAATGGTATAGATATAGAAGTCATCCACAGAGATGTTACAGTTGAAGAGATGGGGGTAGAGAAGACTTTGAAGGAAAAGAATGTAGAATGAGGATAGAAGAGAGGAAATCCCAACATTTAACAG
Seq C2 exon
GTTTGACAGATGAAAAAGTGAAGGCATATCTTTCTCTTCACCCCCAGGTATTAGATGAATTTGTATCTGAAAGTGTTAGTGCAGAGACAGTAGAGAAATGGCTGAAGAGGAAGAACAACAAATCAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000112541_MULTIEX2-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=0.217 A=0.397 C2=0.159
Domain overlap (PFAM):
C1:
NO
A:
PF072008=Mod_r=PU(16.7=92.3),PF147691=CLAMP=PU(4.8=30.8)
C2:
PF072008=Mod_r=FE(59.7=100),PF147691=CLAMP=FE(51.8=100)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCGACATGGAAGATGGACCT
R:
CTTCTGATTTGTTGTTCTTCCTCT
Band lengths:
202-330
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)