HsaEX0046170 @ hg38
Exon Skipping
Gene
ENSG00000112541 | PDE10A
Description
phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772]
Coordinates
chr6:165543440-165662100:-
Coord C1 exon
chr6:165661947-165662100
Coord A exon
chr6:165576412-165576539
Coord C2 exon
chr6:165543440-165543568
Length
128 bp
Sequences
Splice sites
3' ss Seq
TTTGTTTTGTTTTTGTTTAGAAG
3' ss Score
7.37
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
CCAGGCGGCGGCGGCCAAACTCCGCGGCGTCCCCAGGGCGCCAGCTTCGCCCTCGCCGCCGCGGCCGCGCTGCTCTTCGGCTCCGACATGGAAGATGGACCTTCTAATAATGCGAGCTGCTTCCGAAGGCTGACCGAGTGCTTCCTGAGCCCCA
Seq A exon
AAGCTAATGGTATAGATATAGAAGTCATCCACAGAGATGTTACAGTTGAAGAGATGGGGGTAGAGAAGACTTTGAAGGAAAAGAATGTAGAATGAGGATAGAAGAGAGGAAATCCCAACATTTAACAG
Seq C2 exon
GTTTGACAGATGAAAAAGTGAAGGCATATCTTTCTCTTCACCCCCAGGTATTAGATGAATTTGTATCTGAAAGTGTTAGTGCAGAGACAGTAGAGAAATGGCTGAAGAGGAAGAACAACAAATCAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000112541_MULTIEX5-3/6=2-5
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref, Alt. ATG (>10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=0.217 A=0.445 C2=0.169
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000539869fB5053
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCGACATGGAAGATGGACCT
R:
CTTCTGATTTGTTGTTCTTCCTCT
Band lengths:
202-330
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development