HsaEX1027405 @ hg38
Exon Skipping
Gene
ENSG00000112541 | PDE10A
Description
phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772]
Coordinates
chr6:165543440-165711153:-
Coord C1 exon
chr6:165711019-165711153
Coord A exon
chr6:165661947-165662096
Coord C2 exon
chr6:165543440-165543568
Length
150 bp
Sequences
Splice sites
3' ss Seq
CTTCCCCGGCGCCGGCCCAGGCG
3' ss Score
3.43
5' ss Seq
CCAGTAAGT
5' ss Score
9.09
Exon sequences
Seq C1 exon
CCAGCCGCCTCCCCTTCATGCTTAAAGGTGGGAGCAAAGGACCCGCTTTGTTGGCTTTGAGGAGCGGGACAGACCCCCGGGCGCAGATGAGCGATGACCCAGCAGAAGGCACCCTGGACCCCTGCAGTGCGCCAG
Seq A exon
GCGGCGGCGGCCAAACTCCGCGGCGTCCCCAGGGCGCCAGCTTCGCCCTCGCCGCCGCGGCCGCGCTGCTCTTCGGCTCCGACATGGAAGATGGACCTTCTAATAATGCGAGCTGCTTCCGAAGGCTGACCGAGTGCTTCCTGAGCCCCA
Seq C2 exon
GTTTGACAGATGAAAAAGTGAAGGCATATCTTTCTCTTCACCCCCAGGTATTAGATGAATTTGTATCTGAAAGTGTTAGTGCAGAGACAGTAGAGAAATGGCTGAAGAGGAAGAACAACAAATCAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000112541_MULTIEX5-2/6=1-5
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.217 C2=0.169
Domain overlap (PFAM):
C1:
NA
A:
NO
C2:
NO
Main Skipping Isoform:
ENST00000366882fB22177
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGCCTCCCCTTCATGCTTAAA
R:
TGTTGTTCTTCCTCTTCAGCCA
Band lengths:
250-400
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains