HsaEX0046171 @ hg38
Exon Skipping
Gene
ENSG00000112541 | PDE10A
Description
phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772]
Coordinates
chr6:165450242-165466532:-
Coord C1 exon
chr6:165466420-165466532
Coord A exon
chr6:165454578-165454695
Coord C2 exon
chr6:165450242-165450362
Length
118 bp
Sequences
Splice sites
3' ss Seq
AATAAATTTATTTCTTACAGTTC
3' ss Score
7.34
5' ss Seq
AAGGTGGCC
5' ss Score
3.58
Exon sequences
Seq C1 exon
GGTTGCCACGCACCTTCCATTTGTAAAACATGCAATATCTACAAAGAGCAGTAAAGCAAAGCACAATCAAAATGACGTATGCCTGTGCTGACATTCAGAAATACATCTGTTGG
Seq A exon
TTCTGGAGACAGAGAAGCCCAAGGTCAAGGTGCCTGCATCTGGCAAGGACCTTCCTGCTGCATCATCCCATGGCAGAAGGTGGAAGGGCAAGAGATCACGCTTTAGAGAGAGAGGAAG
Seq C2 exon
TACCAAGATACGAATATGCAGGGAGTTGTATATGAACTAAACAGCTATATAGAACAACGGTTGGACACAGGAGGAGACAACCAGCTACTCCTCTATGAACTGAGCAGCATCATTAAAATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000112541-'25-30,'25-29,26-30
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.250 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0159021=GAF=PU(9.2=31.7)
Main Inclusion Isoform:
ENST00000366882fB5054
Main Skipping Isoform:
ENST00000366882fB22177
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTTGCCACGCACCTTCC
R:
CTATTTTAATGATGCTGCTCAGTTCA
Band lengths:
234-352
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development