HsaEX0046173 @ hg38
Exon Skipping
Gene
ENSG00000112541 | PDE10A
Description
phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772]
Coordinates
chr6:165435237-165482343:-
Coord C1 exon
chr6:165482315-165482343
Coord A exon
chr6:165448928-165448977
Coord C2 exon
chr6:165435237-165435377
Length
50 bp
Sequences
Splice sites
3' ss Seq
TTTTCTTATTACTTTGGCAGCCA
3' ss Score
5.95
5' ss Seq
AATGTAAGT
5' ss Score
8.62
Exon sequences
Seq C1 exon
ATGAATCAGCTCCTAAGGAAGTCAGCAGG
Seq A exon
CCACAAAAGCCGATGGATTTGCACTGTATTTCCTTGGAGAGTGCAATAAT
Seq C2 exon
AGCCTGTGTATATTCACGCCACCTGGGATAAAGGAAGGAAAACCCCGCCTCATCCCTGCTGGGCCCATCACTCAGGGCACCACCGTCTCTGCTTATGTGGCCAAGTCCAGGAAAACACTGCTAGTAGAAGACATCCTTGGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000112541_MULTIEX3-3/3=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.890 A=0.000 C2=0.064
Domain overlap (PFAM):
C1:
NO
A:
PF0159021=GAF=FE(11.3=100)
C2:
PF0159021=GAF=FE(32.4=100)
Main Skipping Isoform:
ENST00000366882fB5054
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTCCTAAGGAAGTCAGCAGG
R:
GTTTTCCTGGACTTGGCCACA
Band lengths:
137-187
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development