HsaEX0046173 @ hg19
Exon Skipping
Gene
ENSG00000112541 | PDE10A
Description
phosphodiesterase 10A [Source:HGNC Symbol;Acc:8772]
Coordinates
chr6:165848725-165863850:-
Coord C1 exon
chr6:165863730-165863850
Coord A exon
chr6:165862416-165862465
Coord C2 exon
chr6:165848725-165848865
Length
50 bp
Sequences
Splice sites
3' ss Seq
TTTTCTTATTACTTTGGCAGCCA
3' ss Score
5.95
5' ss Seq
AATGTAAGT
5' ss Score
8.62
Exon sequences
Seq C1 exon
TACCAAGATACGAATATGCAGGGAGTTGTATATGAACTAAACAGCTATATAGAACAACGGTTGGACACAGGAGGAGACAACCAGCTACTCCTCTATGAACTGAGCAGCATCATTAAAATAG
Seq A exon
CCACAAAAGCCGATGGATTTGCACTGTATTTCCTTGGAGAGTGCAATAAT
Seq C2 exon
AGCCTGTGTATATTCACGCCACCTGGGATAAAGGAAGGAAAACCCCGCCTCATCCCTGCTGGGCCCATCACTCAGGGCACCACCGTCTCTGCTTATGTGGCCAAGTCCAGGAAAACACTGCTAGTAGAAGACATCCTTGGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000112541_MULTIEX3-3/3=2-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.064
Domain overlap (PFAM):
C1:
PF0159021=GAF=PU(9.2=31.7)
A:
PF0159021=GAF=FE(11.3=100)
C2:
PF0159021=GAF=FE(32.4=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGAGACAACCAGCTACTCCT
R:
CATAAGCAGAGACGGTGGTGC
Band lengths:
147-197
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)