HsaEX0046864 @ hg38
Exon Skipping
Gene
ENSG00000087157 | PGS1
Description
phosphatidylglycerophosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:30029]
Coordinates
chr17:78378640-78392665:+
Coord C1 exon
chr17:78378640-78378808
Coord A exon
chr17:78382664-78382785
Coord C2 exon
chr17:78392476-78392665
Length
122 bp
Sequences
Splice sites
3' ss Seq
TTTTTTTTTTTTTTTTTGAGATG
3' ss Score
4.74
5' ss Seq
CAGGTGCCC
5' ss Score
5.77
Exon sequences
Seq C1 exon
AGCGGAAGCGGAAGCGGCGAGTCTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGCCTGGCCGCCCAGGGCTGGCCGCGCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAG
Seq A exon
ATGGAGTCCCACTCTGTCGCCCAGGCTGGAGTGCAATGGCACGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCGGAGTAGCTGGGAATACAG
Seq C2 exon
GTCACCATGGCTGTTATTGGCTCCCTTGCTGTCCCCAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCCTGTGTCCAGAAGGCGTGCACCGGTTCCAGTGGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTTCCCCGGCAGAGTTTTTCGAGCTCATGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000087157_MULTIEX1-3/16=C1-4
Average complexity
S
Mappability confidence:
95%=100=95%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.045 A=0.393 C2=0.019
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF130911=PLDc_2=PU(14.7=35.9)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGCGGCGAGTCTCCATG
R:
CTTCTGGACACAGGCAGCAAG
Band lengths:
242-364
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development