HsaEX0051440 @ hg19
Exon Skipping
Gene
ENSG00000119943 | PYROXD2
Description
pyridine nucleotide-disulphide oxidoreductase domain 2 [Source:HGNC Symbol;Acc:23517]
Coordinates
chr10:100152699-100155050:-
Coord C1 exon
chr10:100154953-100155050
Coord A exon
chr10:100153240-100153309
Coord C2 exon
chr10:100152699-100152840
Length
70 bp
Sequences
Splice sites
3' ss Seq
GTGTTGCTTTGTGGATGTAGATG
3' ss Score
6.15
5' ss Seq
AAGGTGCCG
5' ss Score
5.74
Exon sequences
Seq C1 exon
GTGCTGGATCAGTGGTTCGAGTCTGAGCCTTTAAAAGCCACTCTAGCCACAGATGCAGTGATTGGAGCCATGACAAGTCCCCACACTCCGGGGAGTGG
Seq A exon
ATGGGGAAGGATGGTAGCGGTCAAGGCTGACACCTGGATTTCTGTCGGAAACAGAACCTCCTGTTGAAAG
Seq C2 exon
GTATGTGCTGCTGCACCATGTGATGGGGGGCCTGGAGGGAATGCAGGGGGCCTGGGGCTACGTCCAGGGGGGCATGGGTGCCCTCTCTGATGCGATCGCAAGCTCAGCCACCACACATGGAGCAAGCATCTTCACTGAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119943-'15-15,'15-14,17-15
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0126619=DAO=PU(25.2=93.9)
A:
NO
C2:
PF0126619=DAO=FE(50.0=100)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAGTGATTGGAGCCATGACA
R:
GATGCTTGCTCCATGTGTGGT
Band lengths:
174-244
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)