HsaEX0052094 @ hg19
Exon Skipping
Gene
ENSG00000136828 | RALGPS1
Description
Ral GEF with PH domain and SH3 binding motif 1 [Source:HGNC Symbol;Acc:16851]
Coordinates
chr9:129739974-129796793:+
Coord C1 exon
chr9:129739974-129740024
Coord A exon
chr9:129778939-129778994
Coord C2 exon
chr9:129796710-129796793
Length
56 bp
Sequences
Splice sites
3' ss Seq
AGCCCTACCTCCTTTTGCAGGAG
3' ss Score
9
5' ss Seq
TAGGTCAGT
5' ss Score
6.39
Exon sequences
Seq C1 exon
AGCCAGATTACATTAATGGATATACCTGTGTTTAAAGCTATCCAGCCGGAG
Seq A exon
GAGTGAAGCATGGAGGTGGGGACAGACTTCAAGCGATGGAGATATAAACAACCTAG
Seq C2 exon
GAACTAGCCAGCTGTGGATGGAGTAAGAAGGAGAAACACAGTCTTGCCCCTAACGTTGTGGCCTTTACCCGGAGGTTTAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136828_MULTIEX1-4/15=2-5
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0061714=RasGEF=FE(29.1=100)
A:
PF0061714=RasGEF=PD(0.1=0.0)
C2:
PF0061714=RasGEF=FE(49.1=100),PF0061714=RasGEF=PU(0.1=0.0)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGATATACCTGTGTTTAAAGCTATCC
R:
GGTTAAACCTCCGGGTAAAGGC
Band lengths:
116-172
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)