HsaEX0053326 @ hg19
Exon Skipping
Gene
ENSG00000205517 | RGL3
Description
ral guanine nucleotide dissociation stimulator-like 3 [Source:HGNC Symbol;Acc:30282]
Coordinates
chr19:11517398-11526824:-
Coord C1 exon
chr19:11526613-11526824
Coord A exon
chr19:11521929-11522120
Coord C2 exon
chr19:11517398-11517507
Length
192 bp
Sequences
Splice sites
3' ss Seq
CCTAAATTTTCTTTTGACAGTTG
3' ss Score
6.97
5' ss Seq
AAGGTATTT
5' ss Score
7.64
Exon sequences
Seq C1 exon
GGCTGTGGTGTCAGTGCTGGGCTCCTGGCTGCAGGACCACCCTCAGGATTTCCGAGACCCCCCTGCCCATTCGGACCTGGGCAGTGTCCGAACCTTTCTGGGCTGGGCGGCCCCAGGGAGTGCTGAGGCTCAAAAAGCAGAGAAGCTTCTGGAAGATTTTTTGGAGGAGGCTGAGCGAGAGCAGGAAGAGGAGCCGCCTCAGGTGTGGACAG
Seq A exon
TTGTTTCTGGCCAGGTGTTGTGGCACATGCCTATAGTCCCAGCTACTTAGGATGCTGAGATGGGAGGATCTCTTGACTCCGGGAAATCAAAGCTGCCGTGAGCTGTGAGCATGCCCCTGCACTCCAGGCGATAGAGCTGGGGGAAGGAGGAATAGTTGTTTCTTCAAATTGAAATCCAAAGATCTACTCAAG
Seq C2 exon
ACTCTTCAGAGGCCTGCGCGGAGGAAGAGGAAGGGCTCATGCCTCAAGGTCCCCAGCTCCTGGACTTCAGCGTGGACGAGGTGGCCGAGCAGCTGACCCTCATAGACTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000205517_MULTIEX2-5/5=4-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.576 A=0.000 C2=0.638
Domain overlap (PFAM):
C1:
PF0061815=RasGEF_N=PD(29.9=44.4)
A:
NO
C2:
PF0061714=RasGEF=PU(7.6=33.3)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCAGTGTCCGAACCTTTCTG
R:
AAGTCTATGAGGGTCAGCTGCT
Band lengths:
242-434
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)