HsaEX0053326 @ hg38
Exon Skipping
Gene
ENSG00000205517 | RGL3
Description
ral guanine nucleotide dissociation stimulator like 3 [Source:HGNC Symbol;Acc:HGNC:30282]
Coordinates
chr19:11406722-11416148:-
Coord C1 exon
chr19:11415937-11416148
Coord A exon
chr19:11411253-11411444
Coord C2 exon
chr19:11406722-11406864
Length
192 bp
Sequences
Splice sites
3' ss Seq
CCTAAATTTTCTTTTGACAGTTG
3' ss Score
6.97
5' ss Seq
AAGGTATTT
5' ss Score
7.64
Exon sequences
Seq C1 exon
GGCTGTGGTGTCAGTGCTGGGCTCCTGGCTGCAGGACCACCCTCAGGATTTCCGAGACCACCCTGCCCATTCGGACCTGGGCAGTGTCCGAACCTTTCTGGGCTGGGCGGCCCCAGGGAGTGCTGAGGCTCAAAAAGCAGAGAAGCTTCTGGAAGATTTTTTGGAGGAGGCTGAGCGAGAGCAGGAAGAGGAGCCGCCTCAGGTGTGGACAG
Seq A exon
TTGTTTCTGGCCAGGTGTTGTGGCACATGCCTATAGTCCCAGCTACTTAGGATGCTGAGATGGGAGGATCTCTTGACTCCGGGAAATCAAAGCTGCCGTGAGCTGTGAGCATGCCCCTGCACTCCAGGCGATAGAGCTGGGGGAAGGAGGAATAGTTGTTTCTTCAAATTGAAATCCAAAGATCTACTCAAG
Seq C2 exon
GACCTCCCAGAGTTGCCCAAACTTCTGACCCAGACTCTTCAGAGGCCTGCGCGGAGGAAGAGGAAGGGCTCATGCCTCAAGGTCCCCAGCTCCTGGACTTCAGCGTGGACGAGGTGGCCGAGCAGCTGACCCTCATAGACTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000205517_MULTIEX5-4/4=3-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.459 A=0.000 C2=0.551
Domain overlap (PFAM):
C1:
PF0061815=RasGEF_N=PD(29.9=44.4)
A:
NA
C2:
PF0061714=RasGEF=PU(7.6=33.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGACCACCCTCAGGATTTCC
R:
ATGAGCCCTTCCTCTTCCTCC
Band lengths:
253-445
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development