HsaEX0053325 @ hg38
Exon Skipping
Gene
ENSG00000205517 | RGL3
Description
ral guanine nucleotide dissociation stimulator like 3 [Source:HGNC Symbol;Acc:HGNC:30282]
Coordinates
chr19:11406722-11416667:-
Coord C1 exon
chr19:11416614-11416667
Coord A exon
chr19:11415937-11416148
Coord C2 exon
chr19:11406722-11406864
Length
212 bp
Sequences
Splice sites
3' ss Seq
GACCCTGCCTCTCTGGCCAGGGC
3' ss Score
8.87
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
GGTAGAGATCAAGAAGACAGCGGTACAAGATCTGAGCTTCAACAAGAACCTGAG
Seq A exon
GGCTGTGGTGTCAGTGCTGGGCTCCTGGCTGCAGGACCACCCTCAGGATTTCCGAGACCACCCTGCCCATTCGGACCTGGGCAGTGTCCGAACCTTTCTGGGCTGGGCGGCCCCAGGGAGTGCTGAGGCTCAAAAAGCAGAGAAGCTTCTGGAAGATTTTTTGGAGGAGGCTGAGCGAGAGCAGGAAGAGGAGCCGCCTCAGGTGTGGACAG
Seq C2 exon
GACCTCCCAGAGTTGCCCAAACTTCTGACCCAGACTCTTCAGAGGCCTGCGCGGAGGAAGAGGAAGGGCTCATGCCTCAAGGTCCCCAGCTCCTGGACTTCAGCGTGGACGAGGTGGCCGAGCAGCTGACCCTCATAGACTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000205517_MULTIEX5-3/4=2-C2
Average complexity
C1*
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
Show structural model
Features
Disorder rate (Iupred):
C1=0.426 A=0.459 C2=0.551
Domain overlap (PFAM):
C1:
PF0061815=RasGEF_N=FE(16.8=100)
A:
PF0061815=RasGEF_N=PD(29.9=44.4)
C2:
PF0061714=RasGEF=PU(7.6=33.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTAGAGATCAAGAAGACAGCGG
R:
AAGTCTATGAGGGTCAGCTGCT
Band lengths:
196-408
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development