HsaEX0056663 @ hg38
Exon Skipping
Gene
ENSG00000175356 | SCUBE2
Description
signal peptide, CUB domain and EGF like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30425]
Coordinates
chr11:9033626-9047562:-
Coord C1 exon
chr11:9047356-9047562
Coord A exon
chr11:9045712-9045901
Coord C2 exon
chr11:9033626-9033796
Length
190 bp
Sequences
Splice sites
3' ss Seq
TAGGTTTGATTTGTTTCTAGGGG
3' ss Score
5.86
5' ss Seq
CAGGTGTGT
5' ss Score
6.99
Exon sequences
Seq C1 exon
CTTCTTGTGACCTGAGCTGCATCGTAAAGCGAACCGAGAAGCGGCTCCGTAAAGCCATCCGCACGCTCAGAAAGGCCGTCCACAGGGAGCAGTTTCACCTCCAGCTCTCAGGCATGAACCTCGACGTGGCTAAAAAGCCTCCCAGAACATCTGAACGCCAGGCAGAGTCCTGTGGAGTGGGCCAGGGTCATGCAGAAAACCAATGTG
Seq A exon
GGGAGCCAATGTGTCTTGTCTCAGGAGCTCCCAAACACTGGATGAATTCTGTAGCCCTCACAGCATCAAATCAGGTCCAGGTCTGACAGCAATGTTGAAGATTTTACCATGCAGAGAAAACGGCTCAAGCAGTTACCAGTGACATTCCCTCTTGCTGCTGAGGGAGGAAGTGGGTGTAAAGAAGTGTCAG
Seq C2 exon
TCAGTTGCAGGGCTGGGACCTATTATGATGGAGCACGAGAACGCTGCATTTTATGTCCAAATGGAACCTTCCAAAATGAGGAAGGACAAATGACTTGTGAACCATGCCCAAGACCAGGAAATTCTGGGGCCCTGAAGACCCCAGAAGCTTGGAATATGTCTGAATGTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175356_MULTIEX2-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.303 A=0.071 C2=0.034
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF076998=GCC2_GCC3=WD(100=87.9),PF075629=NCD3G=WD(100=46.6)
Main Inclusion Isoform:
ENST00000309263fB6149
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAGTTTCACCTCCAGCTCTC
R:
CTTCAGGGCCCCAGAATTTCC
Band lengths:
256-446
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development