HsaEX0056665 @ hg19
Exon Skipping
Gene
ENSG00000175356 | SCUBE2
Description
signal peptide, CUB domain, EGF-like 2 [Source:HGNC Symbol;Acc:30425]
Coordinates
chr11:9043423-9047401:-
Coord C1 exon
chr11:9047249-9047401
Coord A exon
chr11:9044106-9044303
Coord C2 exon
chr11:9043423-9043502
Length
198 bp
Sequences
Splice sites
3' ss Seq
GGACCCTCCTTTGGTAATAGGTC
3' ss Score
5.7
5' ss Seq
AAGGTCATT
5' ss Score
4.32
Exon sequences
Seq C1 exon
CTTCATCCAATTCTGTGACAACATATGAAACCTGCCAGACCTACGAACGCCCCATCGCCTTCACCTCCAGGTCAAAGAAGCTGTGGATTCAGTTCAAGTCCAATGAAGGGAACAGCGCTAGAGGGTTCCAGGTCCCATACGTGACATATGATG
Seq A exon
GTCAGAGAGAAGAAGAAAAGCAAAGAAGCCTCAGAGAAGTAACCGGTAAGGTAGGAGGAAAACCAAAGAGCATGGTGTCCTGGAAGCTCAGTGAAGAACTGGATCAAGGAGGAGGAGTGACCAGCCAGGTCAAAAGCTACTGATGCATCAAGGAGGATGAAGACCAAGAACTGGCCGTTGGGATTTAACAACATGAAG
Seq C2 exon
AGGACTACCAGGAACTCATTGAAGACATAGTTCGAGATGGCAGGCTCTATGCATCTGAGAACCATCAGGAAATACTTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175356-'27-31,'27-29,29-31
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.006 A=0.383 C2=0.000
Domain overlap (PFAM):
C1:
PF0043115=CUB=PD(41.8=88.5)
A:
NO
C2:
NO
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTCATCCAATTCTGTGACAACA
R:
ATTTCCTGATGGTTCTCAGATGCA
Band lengths:
226-424
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)