HsaEX0056665 @ hg38
Exon Skipping
Gene
ENSG00000175356 | SCUBE2
Description
signal peptide, CUB domain and EGF like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30425]
Coordinates
chr11:9021876-9025854:-
Coord C1 exon
chr11:9025702-9025854
Coord A exon
chr11:9022412-9022756
Coord C2 exon
chr11:9021876-9021955
Length
345 bp
Sequences
Splice sites
3' ss Seq
GGACCCTCCTTTGGTAATAGGTC
3' ss Score
5.7
5' ss Seq
CAGGTAAGT
5' ss Score
10.86
Exon sequences
Seq C1 exon
CTTCATCCAATTCTGTGACAACATATGAAACCTGCCAGACCTACGAACGCCCCATCGCCTTCACCTCCAGGTCAAAGAAGCTGTGGATTCAGTTCAAGTCCAATGAAGGGAACAGCGCTAGAGGGTTCCAGGTCCCATACGTGACATATGATG
Seq A exon
GTCAGAGAGAAGAAGAAAAGCAAAGAAGCCTCAGAGAAGTAACCGGTAAGGTAGGAGGAAAACCAAAGAGCATGGTGTCCTGGAAGCTCAGTGAAGAACTGGATCAAGGAGGAGGAGTGACCAGCCAGGTCAAAAGCTACTGATGCATCAAGGAGGATGAAGACCAAGAACTGGCCGTTGGGATTTAACAACATGAAGGTCATTGCTGGTCTCACCAAGCAGTTTTGGAGGAGTGATGGGGGCCAAAGCTGATTGGACTGGGTTTAAGAGAGAAAGAAAGGAAAAGAATTAGAGACAGTGGGTGCTGACAATTTTTTTAAGGATTTTTGCTGCAAAAGGGAGCAG
Seq C2 exon
AGGACTACCAGGAACTCATTGAAGACATAGTTCGAGATGGCAGGCTCTATGCATCTGAGAACCATCAGGAAATACTTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175356_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.012 A=0.383 C2=0.000
Domain overlap (PFAM):
C1:
PF0043115=CUB=PD(41.8=88.5)
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000309263fB6150
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTCATCCAATTCTGTGACAACA
R:
AAGTATTTCCTGATGGTTCTCAGA
Band lengths:
230-575
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development