HsaEX0065118 @ hg19
Exon Skipping
Gene
ENSG00000146872 | TLK2
Description
tousled-like kinase 2 [Source:HGNC Symbol;Acc:11842]
Coordinates
chr17:60673946-60678181:+
Coord C1 exon
chr17:60673946-60674035
Coord A exon
chr17:60674581-60674619
Coord C2 exon
chr17:60678012-60678181
Length
39 bp
Sequences
Splice sites
3' ss Seq
TGTCTGTTTTATCTTTATAGATT
3' ss Score
10.79
5' ss Seq
ATAGTATGT
5' ss Score
4.41
Exon sequences
Seq C1 exon
GCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTC
Seq A exon
ATTTCCTATTCTGGACCCTCATATGCATGGAATCATATA
Seq C2 exon
GTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146872_MULTIEX1-5/5=4-C2
Average complexity
S
Mappability confidence:
83%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(10.7=100)
A:
PF0006920=Pkinase=PD(11.4=71.4)
C2:
PF0006920=Pkinase=FE(20.4=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCGGATTCATAAAGAGCTGGA
R:
GTCCAGATCATTTCCCTCACAGT
Band lengths:
116-155
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)