HsaEX0067827 @ hg38
Exon Skipping
Gene
ENSG00000123607 | TTC21B
Description
tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:HGNC:25660]
Coordinates
chr2:165890838-165898767:-
Coord C1 exon
chr2:165898695-165898767
Coord A exon
chr2:165894571-165894824
Coord C2 exon
chr2:165890838-165890988
Length
254 bp
Sequences
Splice sites
3' ss Seq
TGTTCTTTATTACACTGTAGACT
3' ss Score
6.52
5' ss Seq
TAAGTAAAT
5' ss Score
1.48
Exon sequences
Seq C1 exon
ATGATGGCTGATCTCATGTTCAGAAAACAAGACTATGAACAAGCAGTGTTTCATTTACAGCAGCTTTTAGAAC
Seq A exon
ACTCCTCGAGTTCAGGGATCACACCATATTCCCAATATCAGACAAAATGCCACACACATGGATGTGGCAACATAGATGTTTATTGGTTGAATGGATCAGTGAATGACTGTAAAACACCAAGTCAATTAAAAACACAGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGCCGTGAGCCAAGATCACACCACTGCACTCCAGCCTCGGTGACAGAGTGAGACTTGGTCTCAAAAACAACCACAAAATTTTAA
Seq C2 exon
ATAATTATATGACATTATCTCGTTTGATTGATCTCCTAAGAAGATGTGGAAAACTCGAGGATGTCCCAAGATTTTTCTCAATGGCTGAGAAACGTAACTCCAGAGCAAAATTGGAACCAGGATTTCAGTATTGTAAAGGACTGTATCTTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123607_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.024 A=0.425 C2=0.000
Domain overlap (PFAM):
C1:
PF145591=TPR_19=PD(5.9=14.3)
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000243344fB7379
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGATGGCTGATCTCATGTTCAGA
R:
GTCCTTTACAATACTGAAATCCTGGT
Band lengths:
213-467
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development